The objective of this study was to evaluate the antinociceptive and sedative effects of epidural administration of romifidine in dairy cattle. Twenty-four dairy cows, divided randomly into four groups (three experimental and one control; n=6) received one of three doses of romifidine (30, 40 or 50 μg/kg) diluted in sterile saline (0.9 per cent) to a final volume of 25 ml or an equivalent volume of sterile saline. Antinociception and its anatomical extent was assessed by applying a standard stimulus (needle pin pricks) in different areas and by applying an electrical stimulus to the flank. The antinociceptive effect of romifidine was produced not only in the tail, anus, perineum, vulva and inguinal area but extended up to the coronary band of the hindlimbs and chest areas. Epidural romifidine induced mild-to-moderate sedation at 30 and 40 μg/kg doses and deep sedation at the 50 μg/kg dose. The antinociceptive and sedative effect was dose-dependent in terms of intensity and duration. Thus, epidural administration of romifidine was effective in providing antinociception and sedation in cattle, and can be used in standing flank and udder surgery in cattle.

In this study, comparative antinociceptive and sedative effects of epidural administration of romifidine and detomidine in buffalo were evaluated. Eighteen healthy adult buffalo, allocated randomly in three groups (two experimental and one control; n=6) received either 50 μg/kg of romifidine or detomidine diluted in sterile saline (0.9 per cent) to a final volume of 20 ml, or an equivalent volume of sterile saline epidurally. Antinociception, sedation and ataxia parameters were recorded immediately after drug administration. Epidural romifidine and detomidine produced mild to deep sedation and complete antinociception of the perineum, inguinal area and flank, and extended distally to the coronary band of the hindlimbs and cranially to the chest area. Times to onset of antinociception and sedation were significantly shorter with romifidine than with detomidine. The antinociceptive and sedative effects were significantly longer with romifidine than with detomidine. Romifidine or detomidine could be used to provide a reliable, long-lasting and cost-effective method for achieving epidural anaesthesia for standing surgical procedures in buffalo. Romifidine induces a longer antinociceptive effect and a more rapid onset than detomidine. Consequently, epidural romifidine may offer better therapeutic benefits in the management of acute postoperative pain.

Romifidine significantly decreased IOP in clinically normal horses and may be used safely for surgery or diagnostic ocular procedures in horses when specific control of IOP is required.

No abstract

Scheduling tasks on heterogeneous resources distributed over a grid computing system is an NP-complete problem. The main aim for several researchers is to develop variant scheduling algorithms for achieving optimality, and they have shown a good performance for tasks scheduling regarding resources selection. However, using of the full power of resources is still a challenge. In this paper, a new heuristic algorithm called Sort-Mid is proposed. It aims to maximizing the utilization and minimizing the makespan. The new strategy of Sort-Mid algorithm is to find appropriate resources. The base step is to get the average value via sorting list of completion time of each task. Then, the maximum average is obtained. Finally, the task has the maximum average is allocated to the machine that has the minimum completion time. The allocated task is deleted and then, these steps are repeated until all tasks are allocated. Experimental tests show that the proposed algorithm outperforms almost other algorithms in terms of resources utilization and makespan.

Seven donkeys raised in different locations in Egypt were found to have a unilateral eye showing motile white worms in the aqueous humor. The parasites were surgically removed from the anterior chamber of the eye in five out of the seven donkeys, and were cleared, mounted and identified as Setaria equina based on light microscopic features. The ocular infection with S. equina reported herein may be the first reported aberrant cases in the Egyptian animals.

No abstract

The purposes of this study were to report the types, causes, and clinical findings of esophageal obstructions in water buffaloes and to verify the role of radiography in diagnosis as well as the evaluation of the proposed treatment management and outcome after treatment. Forty-four buffaloes with esophageal obstruction were used in the study. Esophageal obstruction was significantly more frequent in females than males. Buffaloes at 1-3 years of age were significantly more liable to the disease than those of other ages. Complete obstruction was more frequent than partial obstruction. Intraluminal obstruction was more prevalent than extraluminal. Obstruction at the cervical portion was more frequent than those at pharyngeal region and cardia. Radiography was confirmative in 41 buffaloes (93%). Manipulative treatment was successful in 6 buffaloes (13%) and surgical intervention for cervical esophageal obstructions was carried out by exposure of the cervical esophagus (n = 3), cervical esophagatomy (n = 25), or surgical correction of periesophageal cellulitis (n = 2), while surgical treatment of thoracic esophageal obstruction was carried out via laparorumenotomy (n = 8). In conclusion, early diagnosis, proper application of manipulative or surgical interventions, and postoperative follow-up are the fundamental factors for successful outcomes of esophageal obstruction in water buffaloes.