Hemodialysis leukopenia was studied using various dialyzers and membranes. We found that dialyzers with cellulosic membranes caused marked leukopenia, but in recently developed non cellulosic membranes, its occurrence was significantly less. Additionally, our results showed a newly developed cellulose acetate membrane to correlate well with the non cellulose membranes regarding leukopenia, in spite of it being a derivative of cellulose. The extent of white blood cell decrease seemed to correlate inversely with an increase in the ultrafiltration rate per membrane area of dialyzer. The relationship between leukopenia and hypoxemia was examined also. The results of this investigation are included, however, we feel that more research is necessary before any conclusions can be made.

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ST; TBZ-score was also negatively related to ST duration up to T4. There was no difference in TBZ-score between DMD with or without fractures. L1-L4 Z-score was not influenced by age, HT, BMI, ST, ambulant status and was more stable than TBZ-score over time. In multiple regression analyses, age was the only negative predictor of TBZ-score up to T4 after correction for HtSD and FM% (R2 between 0,54 and 0,20, P's < 0,05), while logistic regression showed that fractures were predicted by BMI SD after correction for TBZ-score, ST (dose or duration) and not by age or HtSD. In conclusion TBZ-score declines in ambulant DMD over time although a high BMI SD may represent the best predictor of fragility fractures in this cohort.