in both class 2 and 3 BRAF mutations. Conclusion: It is evident that different classes of BRAF mutations require distinct treatments, which could even outweigh tumor type. Therefore, we should examine BRAF class in daily clinical practice. Upfront targeting of the MAPK signaling pathway combined with SHP2 inhibitors reveals synergistic interactions, and additional inquisition may pave the way for new treatment options in the most frequently found mutations in BRAF patients.
Background: The diagnosis and treatment of cancer are associated with anxiety of death and cancer recurrence. The outbreak of SARS-CoV-2 pandemic has caused fear and anxiety among cancer patients. Incidence of severe and even fatal complications during SARS-CoV-2 infection is greater in the cancer patients, therefore
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