Purpose:To report three cases of Burkholderia cepacia endophthalmitis following uneventful phacoemulsification surgery.Case Report:Three cases presented with blurriness of vision 2 to 3 weeks following phacoemulsification. Vitreous culture confirmed the diagnosis. Pars plana vitrectomy with intravitreal injection of vancomycin (1 mg/0.1 ml) and ceftazidime (2.25 mg/0.1 ml) was performed. Despite several modalities of treatment, 2 cases did not respond to intravitreal antibiotics and vitrectomy. The first case ended up with phthisis bulbi and the second case underwent evisceration. One case improved after intravitreal injection of the first dose of antibiotic.Conclusion:B. cepacia endophthalmitis is rare and difficult to treat. More studies are necessary to understand the course and outcome of the infection.

Purpose This experimental study was conducted with the aim of evaluating the quantitative change, if any, in the phospholipids and protein contents of lens proteolipids during cataract formation, and to establish whether the phospholipid/protein content of the blood is related to cataractogenesis. Methods A total of 120 human lenses were collected. Phospholipids and protein content in proteolipids of these lenses were estimated biochemically. Blood was examined from total 60 persons. Data obtained were analyzed with the help of the ANOVA program of SPSS software (version 7.5). Results A significant (Po0.01) reduction of proteolipid-bound phospholipids was observed in cataracts as compared with the control lenses. An alteration was also noticed in the protein content of proteolipids in the cataractous lenses. Changes were also observed in serum total phospholipids (Po0.01) and total protein (Po0.01) in cataractous patients. Conclusions As proteolipids are the main constituents of the membranes of lens fibres, the alterations in its phospholipid and protein moieties may be suggestive of the disintegration of lens membranes, which ultimately leads to cataract formation. Gradual and constant variation in serum parameters may be one of the predisposing factors in cataractogenesis.

Purpose: This study analyzed macular thickness (FMT) and retinal nerve fiber layer thickness (RNFL) following phaco-aspiration (PHACO) and small incision cataract surgery (SICS) in adolescent eyes. Methods: Macular thickness and RNFL thickness were measured using optical coherence tomography (OCT) in 52 eyes who underwent PHACO or SICS surgery. OCT measurements were done preoperatively, and on 1st, 14th, 42nd, 84th and 168th postoperative days. Eyes with any other diseases were excluded. Paired sample t-test was used to compare the parameters. Results: The FMT and RNFL thicknesses were found to be higher postoperatively. The SICS group had significantly higher macular thickness (233.06 ± 31.23 μm) than the PHACO group (227.33 ± 28.25 μm) on the 42nd day. The RNFL thickness in SICS was significantly higher than in PHACO and highest on the 84th postoperative day, with mean average value 95.04 ± 16.61 μm and 91.98 ± 18.22 μm respectively. Conclusions: This study shows that cataract surgery increases the macular and RNFL thickness. These increases are significantly higher in the SICS than in PHACO eyes on the 42nd day after surgery, which resolves gradually towards 168th day after surgery. This indicates that phaco aspiration is more preferable surgery then SICS in adolescents with regard to postoperative increase in macular and RNFL thickness.

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