Current energy shortages and environmental crises have compelled researchers to look for inexpensive and sustainable resources that can be obtained via environmentally friendly routes to produce novel functional materials. Biomass has been identified as one of the promising candidates given its availability in large quantities and renewable nature. Among the various feasible synthetic strategies, hydrothermal carbonization (HTC) has been admired for its energy efficiency and ability to synthesize carbonaceous materials for use in a wide range of applications. In this review, the different types of biomass and strategies available for the synthesis of carbon-based materials are discussed. Furthermore, factors influencing the efficiency of each strategy are analyzed and evaluated. Subsequently, the utilization of carbonaceous materials in environmental, catalytic, electrical, and biological applications are reviewed to further demonstrate their functionalities across different fields.
Ag nanoparticles loaded-eggshell catalysts were successfully synthesized by a simple impregnation method, in which the trashy eggshell was served as both biotemplate and support. The eggshell supported Ag catalyst exhibit excellent catalytic activity and stability for benzene oxidation.
Surface nanobubbles emerging at solid-liquid interfaces show extreme stability. In this paper, the stability of surface nanobubbles in degassed water is discussed and investigated by AFM. The result demonstrates that surface nanobubbles are kinetically stable and the liquid/gas interface is gas impermeable. The force modulation experiment further proves that there is a layer coating on nanobubbles. These critical properties suggest that surface nanobubbles may be stabilized by a layer which has a great diffusive resistance.
Albumin-based nanoparticles (NPs) as a drug delivery system have attracted much attention owing to their nontoxicity, non-immunogenicity, great stability and ability to bind to many therapeutic drugs. Herein, bovine serum albumin (BSA) was utilized as a template to prepare Au–BSA core/shell NPs. The outer layer BSA was subsequently conjugated with
cis
-aconityl doxorubicin (DOX) and folic acid (FA) to create Au–BSA–DOX–FA nanocomposites. A list of characterizations was undertaken to identify the successful conjugation of drug molecules and targeted agents. In vitro cytotoxicity using a cell counting kit-8 (CCK-8) assay indicated that Au–BSA NPs did not display obvious cytotoxicity to MGC-803 and GES-1 cells in the concentration range of 0–100 μg/mL, which can therefore be used as a safe drug delivery carrier. Furthermore, compared with free DOX, Au–BSA–DOX–FA nanocomposites exhibited a pH-sensitive drug release ability and superior antitumor activity in a drug concentration-dependent manner. In vivo computed tomography (CT) imaging experiments showed that Au–BSA–DOX–FA nanocomposites could be used as an efficient and durable CT contrast agent for targeted CT imaging of the folate receptor (FR) overexpressed in cancer tissues. In vivo antitumor experiments demonstrated that Au–BSA–DOX–FA nanocomposites have selective antitumor activity effects on FR-overexpressing tumors and no adverse effects on normal tissues and organs. In conclusion, the Au–BSA–DOX–FA nanocomposite exhibits selective targeting activity, X-ray attenuation activity and pH-sensitive drug release activity. Therefore, it can enhance CT imaging and improve the targeting therapeutic efficacy of FR-overexpressing gastric cancers. Our findings suggest that Au–BSA–DOX–FA nanocomposite is a novel drug delivery carrier and a promising candidate for cancer theranostic applications.
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