Background: Stroke remains one of the most important complications of cardiac surgery and occurs in 2.2% after open-heart procedure. It is associated with significant morbidity and mortality. The use of a cerebral protection system during transcatheter aortic valve implantation may be associated with a lower risk of periprocedural strokes, and mortality at 30 days. The aim of the present study was to assess the safety and feasibility of this device in patients at high risk for stroke during open cardiac surgery. Methods: We present six patients with a high risk of perioperative stroke who underwent placement of Sentinel cerebral protection system during various openheart operations between 2018 and 2021.
Results:The system was successfully deployed, and debris was retrieved in all patients. There was no device-related complication or development of ischemic stroke postoperatively. One patient suffered from intracranial hemorrhage due to peri-operative coagulopathy.Conclusions: We demonstrated the feasibility and safety of this hybrid approach with a high debris capture rate. It encourages further study to evaluate the benefits of the Sentinel cerebral protection system in reducing stroke and mortality in selected patients undergoing open-heart surgery.
The new synthetic adenoassociated virus vector Anc80L65 has superior gene transfer efficiency over the adeno-associated virus 9 vector in rat hearts, but other obstacles remain.
Background and Aims: Epithelioid hemangioendothelioma is a rare malignant vascular tumor with limited literature.
Aims:We reported an innovative endovascular biopsy of the right innominate vein tumor.Materials and Methods: Endovascular suction thrombectomy was performed with multipurpose catheter and constant negative pressure under fluoroscopic guidance.Results: Epithelioid hemangioendothelioma was diagnosed preoperatively and a complete margin-free tumor resection with patch repair of the right innominate vein was achieved via sternotomy.Discussion: Preoperatively diagnosis is usually not available due to lesions' location.Identifying malignant vascular tumors becomes valuable to guide the surgical treatment.Conclusions: In this case report, this innovative endovascular approach led to a rare preoperative diagnosis of EHE and subsequent margin-free resection.
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