ABSTRAK Latar belakang: Brotowali (Tinospora crispa L.) merupakan salah satu tanaman obat yang memiliki berbagai manfaat untuk pengobatan malaria, hepatitis, diabetes mellitus, dan rematik. Brotowali mengandung senyawa kimia antara lain glikosida pikroretosid, palmatin, alkaloid berberin, dan zat pahit pikroretin. Banyaknya manfaat brotowali di kehidupan sehari-hari untuk mencegah dan mengobati berbagai penyakit maka tumbuhan ini berpotensi dikembangkan menjadi sediaan calon obat dalam bentuk ekstrak, sehingga perlu dilakukan standarisasi mutu ekstrak. Diantara parameter mutu ekstrak adalah kadar sari larut air, dan kadar sari larut etanol. Salah satu factor yang mempengaruhi mutu ekstrak adalah ukuran simplisia. Tujuan penelitian ini adalah untuk mengukur pengaruh ukuran simplisia batang brotowali terhadap rendemen, kadar sari larut air, dan kadar sari larut etanol ekstrak. Metode: Jenis penelitian adalah penelitian eksperimental. Batang brotowali dibagi menjadi dua ukuran yaitu dirajang dan diserbuk, lalu masing-masing dimaserasi dengan etanol 96% dan dikentalkan dengan rotary evaporator. Ekstrak masing-masing dilakukan uji rendemen, kadar sari larut air, dan kadar sari larut etanol. Hasil: Ekstrak etanol batang brotowali dari simplisia yang dirajang mempunyai rendemen ekstrak sebesar 6,0775%, kadar sari larut air sebesar 27,5950% dan kadar sari larut etanol sebesar 33,3123%. Sedangkan dari simplisia yang diserbuk mempunyai rendemen ekstrak sebesar 10,0918%, kadar sari larut air sebesar 60,7335% dan kadar sari larut etanol sebesar 39,4689%. Ekstrak etanol dari batang brotowali yang diserbuk mempunyai rendemen, kadar sari larut air, dan kadar sari larut etanol yang lebih besar dibandingkan ekstrak etanol dari batang brotowali yang dirajang. Kata kunci: Rendemen; Kadar sari larut air; Kadar sari larut etanol; Batang brotowali; Ukuran simplisia Abstract Background: Brotowali (Tinospora crispa L.) is one of the medicinal plants that has various benefits for treatment. Brotowali contains chemical compounds such as glycosides picroretoside, berberine alkaloids and picroretin bitter substances. With the many benefits of this brotowali to prevent and treat various diseases, this plant has the potential to be developed into a prospective drug preparation in the form of extracts, so it is necessary to standardize the quality of the extract. Among the quality parameters of the extract were the water soluble extract content and the ethanol soluble extract content. One of the factors that affect the quality of the extract is the size of the simplicia. The purpose of this study was to measure the effect of brotowali stem simplicia size on yield, water soluble extract content, and ethanol soluble extract content. Methods: This type of research is experimental research. Brotowali stems are divided into two sizes, namely chopped and powdered, then each macerated with 96% ethanol and thickened with a rotary evaporator. Each extract was tested for yield, water soluble extract content, and ethanol soluble extract content. Results: The ethanol extract of brotowali stems from chopped simplicia had an extract yield of 6.0775%, water soluble extract content of 27.5950% and ethanol soluble extract content of 33.3123%. Meanwhile, the powdered simplicia had an extract yield of 10.0918%, water soluble extract content of 60.7335% and ethanol soluble extract content of 39.4689%. The ethanol extract from the powdered brotowali stem had a higher yield, water soluble extract content, and ethanol soluble extract content than the ethanol extract from chopped brotowali stem. Keywords: Yield; Water soluble extract content; Ethanol soluble extract content; Brotowali stem;Simplicia size
Background: The form of soap that has not been widely circulated in the market is soap in sheet form or in paper form. The sheet form will provide an advantage, which is easy to store and can be carried anywhere, and the use of one sheet at a time can maintain the quality of the soap. One of the natural active ingredients that have an antibacterial effect are the leaves of the mother-in-law's tongue leaf plant (Sansevieria trifasciata Prain) and the aloe vera (Aloe vera L.) leaf extract. This study aims to formulate the Ethanol Extract of Aloe Vera Leaf (Sansevieria trifasciata Prain) and Aloe Vera Leaf Ethanol Extract (Aloe vera L.) into paper soap preparations that meet the requirements. Methods: The method used is experimental by making paper soap from mother-in-law's aloe leaf extract and aloe vera extract by making formulas I, II, III with 10%, 15% and 20% percentages of aloe vera extract, while the percentage of aloe vera extract is 3%, 6 % and 9%. And evaluation of the preparation was carried out for 28 days, and Test the effectiveness of Gram positive bacteria (Staphylococcus aureus) and Gram negative bacteria (Escherichia coli). Results: During 28 days of storage, the preparation of soap made from pH-stable paper tends to decrease as well as foam stability and free fatty acid content, but it still meets the requirements of SNI. The results of the organoleptic test of methamphetamine preparations made from paper did not change the smell and color, and did not irritate the skin, And has an inhibitory effect on the growth of Staphylococcus aureus bacteria. Conclusion: Paper soap with ethanol extract of mother-in-law's tongue (Sansevieria trifasciata p.) and ethanolic extract of aloe vera leaf (aloe vera L.) can be formulated into paper-based soap preparations that are stable and meet the specifications required by the Indonesian National Standard (SNI) and are able to inhibit growth. Staphylococcus aureus and Escherichia coli. The most optimal formula in Formula II with varying concentrations of a mixture of 15% aloe vera leaf ethanol extract and 6% aloe vera leaf ethanol extract .
ABSTRAK Sebaran virus corona di dunia hingga kini belum juga mereda, bahkan telah muncul varian baru seperti varian Delta yang merebak dan menyebabkan lonjakan kasus dibeberapa negara diantaranya Amerika Serikat, India, Brazil, prancis dan Rusia. Tingginya lonjakan kasus Covid-19 pada medio 2021 di banyak negara secara umum dipicu oleh ketidakdisiplinan masyarakat dalam menjalankan protokol kesehatan, munculnya varian virus yang lebih menular, dan program vaksinasi yang belum terlaksana sepenuhnya.Tujuan pengabdian masyarakat ini adalah menggugah kesadaran masyarakat pentingnya memutus mata rantai penyebaran Covid-19 dengan melakukan vaksinasi dan tetap menerapkan protokol kesehatan serta mampu mengoptimalkan potensi sumber daya yang ada di masyarakat Desa Pipa Putih Ogan Ilir. Pendidikan kesehatan yang dilakukan berupa ceramah, tanya jawab, pemutaran video dan simulasi. Penerimaan masyarakat dapat terlihat dari antusiasme mengikuti kegiatan hingga akhir. Pendidikan kesehatan pada desa Pipah Putih mendapatkan hasil yaitu terwujudnya peningkatkan derajat kesehatan masyarakat yang tanggap dan tangguh. Kata Kunci: Pendidikan Kesehatan , Penerapan Protokol Kesehatan, Adaptasi Kebiasaan Baru ABSTRACT Until now, the spread of the coronavirus in the world has not subsided, in fact, new variants have emerged such as the Delta variant which has spread and caused a spike in cases in several countries including the United States, India, Brazil, France, and Russia. The high spike in Covid-19 cases in mid-2021 in many countries was generally triggered by public indiscipline in implementing health protocols, the emergence of more infectious virus variants, and vaccination programs that have not been fully implemented. The purpose of this community service is to raise public awareness of the importance of breaking the chain. the spread of Covid-19 by vaccinating and continuing to apply health protocols and being able to optimize the potential of existing resources in the community of Pipa Putih Ogan Ilir Village. Health education is carried out in the form of lectures, questions, and answers, video screenings, and simulations. Public acceptance can be seen from the enthusiasm for participating in the activity until the end. Health education in Pipah Putih village has resulted in the realization of an increase in the health status of a responsive and resilient community. Keywords: Health Education, Implementation of Health Protocols, Adaptation of New Habits
Cashew is a plant that has antioxidant benefits. Extraction by hot method is more perfect and the extraction process is faster than cold extraction. This study aims to compare the antioxidant activity of cashew leaf extract obtained by means of soxhletation and reflux. This research is an experimental method by measuring the percentage of attenuation on DPPH and IC50 of cashew leaf extracts extracted by soxhletation and reflux methods. The result of this research is that the antioxidant activity of soxhletation cashew leaf extract is 9.08 ppm and reflux is 9.56 ppm. It was concluded that the antioxidant activity of soxhletation cashew leaf extract was greater than that of reflux cashew leaf extract.
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