Background: Extra-hepatic portal vein obstruction (EHPVO) due to portal vein thrombosis is an important cause of portal hypertension in several region including India. The cause of thrombosis in these patients remains unclear. Objective of the study was to study the demographic features, etiology, clinical, laboratory findings with special reference to thrombophilic factors like protein C, protein S and antithrombin III deficiency in children with EHPVO.Methods: The prospective analysis of 62 patients of EHPVO (<14 years of age) was done in the Department of Hepatology, SCB medical College, Cuttack. After detailed history, clinical examination, Ultrasound abdomen /color Doppler and Upper GI endoscopy, the subjects were analyzed for any deficiency of thrombophilic factors like protein C, protein S and antithrombin III.Results: A total of 62 patients (37 Male, 25 Female) with mean age of 8.3+3.1 years were studied. Growth retardation was present in the form of wasting (alone) 20.9%, stunting (alone) 25.8% and both wasting and stunting was found in 9.8% cases. History of neonatal, umbilical sepsis and umbilical vein catheterization was found in 15.9% and 10.2% of cases respectively. Haemorrhage from oesophageal varices was prevalent symptoms in 85.9% patients. Splenomegaly was found in 91.9% patients and ascites in 9.4% patients. 47 patients studied for protein C, S and antithromibin III. 14 patients were found to have thrombophilia: protein C deficiency in 9, protein S deficiency in 8, Antithrombin III deficiency in 6.Conclusions: The etiology of EHPVO in the majority of patients remain still unclear. It is commonly associated impaired somatic growth. The risk of EHPVO increases in the presence of thrombophilia, resulting from deficiency of naturally occurring anticoagulant proteins like Protein C, Protein S and Antithrombin III.
Hepatitis is a highly infectious disease caused by a number of viruses. A study was undertaken in a ward of Cuttack City, where suddenly a number of cases of Jaundice reported. A team from the departments of Community Medicine visited the ward and collected the data by door to door survey. A total of 281 houses were surveyed and data was obtained. There were a total number of 55 jaundice cases. The cases reported with symptoms of fever, anorexia, yellow sclera and yellow urine. 64.3% of cases used Municipality source of water. 7.3% used the water for drinking purpose after boiling and filtration. 28% of houses did not have sanitary latrine, 85.5% from all the jaundice cases used the water for drinking purposes. The young adults were mostly affected. The cause of jaundice could be due to contamination of water supply by Municipality because of leakage and the causative agent was Hepatitis E Virus.
Background: Non-communicable diseases (NCDs) are ragging reality of today’s world and have moved up the priority list of most countries worldwide including India. Objectives were to find out prevalence of different types of strokes among the patients admitted in neurology department of SCB medical college, to study socio-clinical profiles of admitted stroke patients and to find out associated risk factors with different types of strokes.Methods: Cross-sectional hospital-based study in neurology ward of SCB MCH, Cuttack, Odisha in 2019-20.Results: The mean age 60.93±12.8, males are more affected, 60-69 years were more affected, 76% were ischemic strokes, 85% cases weakness of limbs reported, hypertension, diabetes, alcoholism, smoking, dyslipidemia were major risk factors. Hypertension and smoking found to be highly significant in case of young stroke patients.Conclusions: Major modifiable risk factors were hypertension (63.3%) followed by alcohol intake 53.9%.
Introduction: Wilson’s Disease is an autosomal recessive disease. It is characterized by degenerative changes in the brain, liver and Kayser-Fleischer Rings in the Cornea. It is observed with the prevalence of approximately 1:3000 among all ethnic groups. Aims & Objectives: To study the clinical profile and therapeutic aspects of Wilson’s Disease. Material and Methods: It was a prospective observational study conducted in the department of Hepatology of SCB Medical College & Hospital, in Cuttack city of Odisha. Patients were followed up after 6 month and response to treatment was observed. Results: Most patients were in age group 11-15 years (43%), male, female ratio being 2:1. 64% patients had hepatic presentations, 11% patients had neurological presentations and 25% of patients had both hepatic & neurological presentations. The hepatic presentations were jaundice in 79% of cases followed by Ascites and pedal edema in 75% of cases each, 29% patients were having UGI bleeding. Among the 28 patients 68% presented with KF Rings, 16% patients had child A, 28% had Child B and 56% patients had Child C cirrhosis. Conclusion: The commonest presentation of Wilson’s disease was Chronic Liver Disease.
BACKGROUND: World Health Organization (WHO) has dened Low Birth Weight (LBW) as birth weight less than 2,500 grams irrespective of
gestational age. Overall, it is estimated that 15% to 20% of all births worldwide are LBW, representing more than 20 million births a year.
OBJECTIVE isto assess the socio-demographic and maternal risk factor associated with LBW babies. METHOD: A hospital based case
controls study with 107 mothers of LBWbabies as case and 214 mothers of normal weight babies as control who delivered at DHH Jagatsinghpur.
RESULT:Rural area, working women, low SEC status, low BMI, associated chronic disease, anemia, less no of ANC check up etc were associated
risk factor for LBW babies. Occurrence of hypothermia, hypoglycemia, refusal to feed, respiratory distress, neonatal sepsis etc. early neonatal
complications were more in LBWbabies as compared to babies having normal birth weight.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.