A new approach, involving the anchoring-unanchoring of a fluorophore, has been developed for the detection of Au-species. The fluorescent probe was found to be highly selective for sensing gold species in the presence of several other metal ions. A successful application to bioimaging has also been demonstrated with A549 lung cancer cells.

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Herein, a new reaction-based fluorescent probe 6-cyanonaphthalen-2-yl 4-oxopentanoate (NPCN-OLV) was designed and synthesized for the detection of hydrazine (N 2 H 4 ). The addition of N 2 H 4 to a solution of probe NPCN-OLV resulted in a striking fluorescence increase, moreover, it is complemented by a visual color change from colorless to yellow. Importantly, this distinct color response indicates that probe NPCN-OLV could be implemented as a colorimetric tool for the recognition of N 2 H 4 . N 2 H 4 can be detected quantitatively. The lower detection limit for the N 2 H 4 is 5 μM where actual fluorescence observed and gradually increased with concentration. The probe NPCN-OLV served the selective visible naked-eye sensing of hydrazine in the presence of representative metal ions and common anions.Along with that we have also demonstrated the use of paper strip for the qualitative detection of hydrazine, which showed an evident color change (sky blue) only with the paper strip with hydrazine in PBS buffer.

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