ObjectivesTo determine attention performance of medical students after sleep deprivation due to night shift work.MethodsProspective cohort design. All seventh, eighth and ninth semester students were invited to participate (n= 209). The effectiveness and concentration indices (d2 Test for attention, dependent variable) from 180 students at 3 evaluations during the semester were compared. Eighth and ninth semester students underwent their second evaluation after a night shift. The independent variables were nocturnal sleep measurements.ResultsNo differences in nocturnal sleep hours during the previous week (p=0.966), sleep deprivation (p=0.703) or effectiveness in the d2 Test (p=0.428) were found between the groups at the beginning of the semester. At the beginning and the end of the semester, the d2 Test results were not different between groups (p=0.410, p=0.394) respectively. The second evaluation showed greater sleep deprivation in students with night shift work (p<0.001). The sleep deprived students had lower concentration indices (p<0.001).The differences were associated with the magnitude of sleep deprivation (p=0.008). Multivariate regression analysis showed that attention performance was explained by sleep deprivation due to night shift work, adjusting for age and gender. Students with sleep deprivation had worse concentration than those without.ConclusionsSleep deprivation due to night shift work in medical students had a negative impact on their attention performance. Medical educators should address these potential negative learning and patient care consequences of sleep deprivation in medical students due to night shifts.
BackgroundPapular urticaria is a chronic inflammatory disease caused by exposure to arthropod bites. The disease has been reported in children attending medical centers, but the causes as the risk factors associated with the disease have not been established. The objective of this study was to determine the prevalence of papular urticaria caused by flea bite and identify the risk factors in children between 1 to 6 years of age in Bogotá D.C, between March 2009 and June 2011.MethodsA cross-sectional, two-stage, clustered study using random probability sampling and stratified with proportional allocation was carried out in children (1–6 years of age) in educational institutions in Bogotá D.C. to determine the prevalence of the disease. Children underwent a dermatological examination by general practitioners with a previous training. Furthermore, digital photographs of skin lesions were taken for further confirmation of the diagnosis by dermatologists. A structured survey was completed by the parents or caregivers, and it was evaluated using an unconditional logistic regression to identify factors associated with the disease.ResultsA total of 2437 children were included in the study. The prevalence of papular urticaria caused by flea bite in this population was 20.3% (CI 95%: 18.2 to 22.5%). The major risk factors associated with the disease were the presence of fleas in households (OR 1.74, CI 95%: 1.35 to 2.25), using mattresses without springs (OR 1.73, CI 95%: 1.20 to 2.50), the use of daily public transportation to carry the children to the educational institutions (OR 1.76, CI 95%: 1.07 to 2.89), having a soil/earth floor in the main bedroom (OR 6.81, CI 95%:1.16–39.96), and having siblings with a history of atopic dermatitis (OR 1.76 CI 95%: 1.07–2.89).ConclusionsA high prevalence of papular urticaria caused by flea bite was found in Bogotá D.C. The main factors associated with the disease might be modified with the implementation of prevention, control strategies in housing, educational institutions, and public transportation.
RESUMENObjetivos Caracterizar pacientes con intento suicida atendidos en Psiquiatría en la Unidad Primaria de Atención (UPA) La Estrella entre octubre-2004 y octubre-2005 y determinar la persistencia de ideación suicida, los factores asociados así como factores predictores. Métodos Caracterización inicial de pacientes con intento suicida (n=156). Diseño posterior de casos y controles (n=77) según persistencia de ideación suicida (n=27). Se determinaron los factores asociados y la predicción del riesgo suicida con un modelo multivariado. Resultados Los casos aumentaron de 6 en octubre-2004 hasta 10 en octubre-2005, con promedio mensual: 12 ± 3,6 casos. El 80 % tenía 30 años o menor edad, 66,7 % eran mujeres, 24,4 % estudiantes y 20,5 % desempleados. Como desencadenantes: disfunción familiar y conflictos de pareja en 35,2 % cada uno. El 49 % consumió alcohol previo al intento suicida. La persistencia de ideación suicida se asoció con tener 31 años o más, desempleo, más de un intento suicida previo, conflictos sin resolver y disfunción familiar. La no resolución de conflictos, OR=106,7 (IC 95 %: 6,8, 1668,4) y la disfunción familiar, OR=11,05 (IC95 %: 1,7, 71,2) fueron predictores de la persistencia de ideación suicida en el modelo de regresión logística. Conclusión La no resolución de conflictos y la disfunción familiar, predictores de la persistencia de ideación suicida en sujetos con intento suicida, el consumo de alcohol y otros factores asociados podrían controlarse con programas de prevención y promoción de salud mental.Palabras Clave: Intento de suicidio, conflicto, relaciones familiares, factores de riesgo, Colombia (fuente: DeCS, BIREME). Granada -Modelo movilización actividad física L ABSTRACTObjective Characterising patients attempting suicide who were evaluated by psychiatry at the Primary Care Unit (PCU) "La Estrella" from October/2004 to October/2005 and determining persistent suicidal ideation and associated factors. Methods An initial description of attempted suicide patients (n=156). A subsequent case control study (n=77) determined persistent suicidal ideation cases (n=27). A multivariate model was used for determining the remaining factors associated with persistent suicide ideation. Results Cases increased from 6 in October/2004 to 10 in October/2005, average 12 ± 3,6 cases monthly. 80 % were aged 30 or younger, 66,7 % were female, 24,4 % were students and 20,5 % were unemployed. 35,2 % suffered family dysfunction and 35.2% had conflicts between couples as precipitant factors. 49 % had consumed alcohol prior to the suicide attempt. Persistent suicidal ideation was associated with being 31 years old or older, being unemployed and having a higher number of previous suicide attempts, unresolved conflicts and family dysfunction. Logistical regression revealed unresolved conflicts (OR=106.7; 6,8; 1 668,4 95 % CI) and family dysfunction (OR=11.05; 1,7; 71,2 95 % CI) as predictor variables for persistent suicidal ideation. Conclusion Unresolved conflicts and family dysfunction were found to be predicto...
Background This meta-analysis presents evidence regarding the diagnostic accuracy of mammaglobin detected using the RT-PCR technique, related to the presence of sentinel node metastasis in breast cancer patients. Methods The following databases were consulted: Cochrane, Lilacs, Scielo, Hinary, PubMed, Elsevier, Embase, ProQuest, the Universidad del Rosario´s Centro de Recursos Para el Aprendizaje y la Investigación (CRAI-UR) [Resource Center for Learning and Research], and the Google Scholar search engine. The quality of the studies was assessed using the QUADAS-2 and CASpe tools. The selected studies presented the necessary data to calculate diagnostic validity index of mammaglobin detection using RT-PCR, compared with the reference standard test. Global values for the sensitivity, specificity, positive predictive value, negative predictive value, probability ratios, diagnostic ORs, and summary ROC curves of this meta-analysis were obtained using the Meta-DiSc 1.4 program. Results Initially, 731 articles were obtained; but only 25 were included in the meta-analysis. Sensitivity was 84% (95% CI: 83% - 86%), and specificity was 92% (95% CI: 91% - 93%). Positive and negative predictive values were 9.26 (95% CI: 6.47–13.26) and 0.17 (95% CI: 0.13–0.23), respectively. The diagnostic OR was 66.34 (95% CI: 42.52–103.52). The predictive area under the sROC curve was 94.78 (Q = 0.8876). Conclusions The evaluated diagnostic index showed that the expression of the mammaglobin biomarker has diagnostic prediction for detecting lymph node metastasis in breast cancer patients, when analyzed using RT-PCR, although more than 50% heterogeneity was found.
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