We analyse new genomic data (0.05–2.95x) from 14 ancient individuals from Portugal distributed from the Middle Neolithic (4200–3500 BC) to the Middle Bronze Age (1740–1430 BC) and impute genomewide diploid genotypes in these together with published ancient Eurasians. While discontinuity is evident in the transition to agriculture across the region, sensitive haplotype-based analyses suggest a significant degree of local hunter-gatherer contribution to later Iberian Neolithic populations. A more subtle genetic influx is also apparent in the Bronze Age, detectable from analyses including haplotype sharing with both ancient and modern genomes, D-statistics and Y-chromosome lineages. However, the limited nature of this introgression contrasts with the major Steppe migration turnovers within third Millennium northern Europe and echoes the survival of non-Indo-European language in Iberia. Changes in genomic estimates of individual height across Europe are also associated with these major cultural transitions, and ancestral components continue to correlate with modern differences in stature.
Typologies have always played an important role in urban planning and design practice and formal studies have been central to the field of urban morphology. These studies have predominantly been of a historical-qualitative nature and do not support quantitative comparisons between urban areas and between different cities, nor offer the precise and comprehensive descriptions needed by those engaged in urban planning and design practice. To describe contemporary urban forms, which are more diffuse and often elude previous historic typologies, systematic quantitative methods can be useful but, until recently, these have played a limited role in typo-morphological studies. This paper contributes to recent developments in this field by integrating multi-variable geometric descriptions with inter-scalar relational descriptions of urban form. It presents typologies for three key elements of urban form (streets, plots and buildings) in five European cities, produced using statistical clustering methods. In a first instance, the resulting typologies contribute to a better understanding of the characteristics of streets, plots and buildings. In particular, the results offer insight into patterns between the types (i.e., which types are found in combination and which not) and provide a new large scale comparative analysis across five European cities. To conclude, we establish a link between quantitative analysis and theory, by testing two well-known theoretical propositions in urban morphology: the concept of the burgage cycle and the theory of natural movement.
There is an epistemological divide in the field of road network analysis, concerning the way network distance should be conceptualized. On one hand, the generality of studies in the field adopt metric distance as a self-evident choice. On the other, space syntax studies adopt a different distance concept, namely that of angular distance, which ignores actual physical lengths. Theoretically, these two distance concepts imply quite different assumptions. Analytically, they produce also different results.In this paper we assess the differences between these two network distance concepts, using a model of the UK's complete road network (2,031,971 nodes) and a very large dataset of vehicular movement counts (20,752 locations). We describe the statistical associations between observed vehicular flows and the betweenness centrality of the road-network nodes where such flows were measured, the latter calculated with metric and angular distance functions, across a number of increasing radii. Relations to road capacity are also discussed in principal roads where this is known.The geographical comprehensiveness of our model and the size of our movement sample allow us to state, with unprecedented statistical validity, the clear outperformance of angular distance over metric distance, in what concerns the strength of the studied correlations. This is true for all types of roads (urban and non-urban) and for all motorized vehicles, representing 99.05% of the total traffic; the remaining 0.95% correspond to pedal cycles, which yielded inconclusive results. We also demonstrate the existence of two distinct regimes of association between movement and centrality, conspicuous in cities but altogether absent in non-urban areas, which represent new evidence supporting space syntax's dual model of urban form.
We analyse new genomic data (0.05-2.95x) from 14 ancient individuals from Portugal distributed from the Middle Neolithic (4200-3500 BC) to the Middle Bronze Age (1740-1430 BC) and impute genomewide diploid genotypes in these together with published ancient Eurasians. While discontinuity is evident in the transition to agriculture across the region, sensitive haplotype-based analyses suggest a significant degree of local hunter-gatherer contribution to later Iberian Neolithic populations. A more subtle genetic influx is also apparent in the Bronze Age, detectable from analyses including haplotype sharing with both ancient and modern genomes, D-statistics and Y-chromosome
Objective: To investigate the quality of life of community health workers and associate the results with socioeconomic variables. Methods: Cross-sectional study conducted with 153 Community Health Workers of the Brazilian Northeast region active workers in December 2014. We used self-report instrument composed of sociodemographic profile and the 36-Item Short Form Health Survey (SF-36) questionnaire. To determine the domains of the SF-36, mean and standard deviation, the Mann-Whitney test was used, with a 0.05 significance level. Results: Most agents were women (80.4%) aged 42 years (±8.01); 64.1% who worked in that position for at least 10 years. The Bodily Pain and General Health Perception domains were the most affected ones. In the first domain, the low rates of means were associated with women over forty years old, less than twelve years of study and more than ten years as a Community Health Worker. In the second domain, the lowest mean levels were associated with women living with more than four people in the household. Conclusion: We detected a loss in quality of life of community health workers, demonstrating low means in the investigated areas, with lower scores for Pain and General Health Perceptions. Several socioeconomic factors interfere with the health and quality of life of workers, as being female, aged over 40, low education level, higher family composition and greater working time.
(24,44%). Houve predomínio de casos no sexo masculino (51,06%), cor parda (55,65%), faixa etária de 10-14 anos (60,22%) e com escolaridade média de 6-11 anos (59,8%). A maioria das formas clínicas notificadas foi do tipo indeterminada (40,13 %), tendo como predominante o grau de incapacidade física II (21,1 %). Não foram estatisticamente significantes as diferenças proporcionais entre as formas clínicas (p-valor=0,056); ao passo que a escolaridade apresentou associação significativa (p<0,0001) com a ocorrência da doença entre menores de 15 anos de idade. Conclui-se que a hanseníase continua uma doença de fácil disseminação, considerando a frequência de casos novos. PALAVRAS-CHAVE: Hanseníase. Incidência. Menores de 15 anos. INCIDENCE OF LEPROSY IN PATIENTS AGED 15 OR YOUNGER CARED IN THE MUNICIPALITY OF IMPERATRIZ, MARANHÃO, BETWEEN 2004 AND 2010ABSTRACT: The purpose of this study was to estimate the global incidence and cases indexes of leprosy and to design the socio--demographic profile in children under 15 years of age in the municipality of Imperatriz, in the state of Maranhão, Brazil. A longitudinal retrospective study of leprosy cases in the municipality was performed, using information generated by the disease reports in SINAN NET. There was a predominance of male (51.06%), brown color (55.65%), aged between 10-14 years (60.22%), and average schooling of 6-11 years (59.8%). Most of the clinical forms reported were of the indeterminate type (40.13%), with predominance of physical incapacity degree II (21.1%). The proportional differences between the clinical forms (p-value = 0.056) were not statistically significant, while schooling presented a significant association (p <0.0001) with the occurrence of the disease among children under 15 years of age. It can be concluded that leprosy remains a disease with easy spread when considering the rate of new cases.
Robust quantitative descriptions of the social and physical characteristics of urban contexts are essential for assessing the impacts of urban environments on other, potentially dependent variables. Common methodologies used for that purpose, however, are either coarse or suffer from biasing effects. At the social level, the use of indicators encoded into pre-defined areal units, makes results prone to the Modifiable Areal Unit Problem. At the physical level, the adopted morphological indicators are usually highly aggregated descriptors of urban form. Moreover, there is a lack of explicit methodologies for the purposive sampling of urban contexts with specific combinations of social and physical characteristics, which—we argue—may be more effective than probabilistic sampling, when exploring phenomena as elusive as the effects of urban contextual factors. This article presents a set of GIS-based methods for addressing these issues, based on: a) local indicators of spatial association; b) detailed quantitative morphological descriptions, coupled with unsupervised classification techniques; and c) purposive sampling strategies carried out on the data generated by the proposed context characterization methods (a and b). The methods are illustrated through the characterization of the urban contexts of the 77 state-sector secondary schools in Liverpool, but are generalizable across all categories of urban objects and are independent of the geographical context of implementation.
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