Immunoassays are generally antigen antibody analytical methods used for quantitative or for qualitative analysis. They are most commonly used for diagnostic purposes, drug monitoring in pharmacokinetic studies and in the quality control. ELISA is the most common used immunoassay where an enzyme is linked to detect the antibodies in the blood. ELISA tests are more accurate compared to other antibody-assays as it yields quantitative results. This review article describes ELISA and its applications, types and limitations.
Desmoplastic Ameloblastoma accounts for 4% to 13% of all ameloblastomas and is a rare variant with high rate of recurrence. The desmoplastic variant of ameloblastoma usually appears in the anterior and premolar regions and sometimes resembles a benign fibro-osseous lesion showing a mixed radiolucent and radiopacity in the radiographic examination. Malignant transformation with repeated postsurgical recurrences have also been reported. In this paper we present a case of a 22-year-old female with swelling in the left upper jaw which turned out to be desmoplastic ameloblastoma. The pathologist and the clinician should be aware of the concepts and the association with malignant transformation and spread of the lesion in order to deliver appropriate treatment and to avoid further recurrences of the leison.
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