RIT with IFA WBE for IFA hypersensitivity is both safe and efficacious; the rate of mild systemic reactions is low. Premedication is not necessary, inasmuch as prophylactic pretreatment with antihistamines and steroids did not reduce the systemic reaction rate associated with RIT.
Recent work has focused on achieving more rapid protection in hypersensitive patients given the high sting attack rates in endemic area with sensitization occurring early in life among those exposed to the imported fire ant.
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