Perception and practice of sublingual immunotherapy among practicing allergists in the United States: a follow-up survey

Comprehensive Study of Patients’ Compliance with Sublingual Immunotherapy in House Dust Mite Perennial Allergic Rhinitis

“…However, this method is associated with several problems, such as inconvenience, invasiveness, and moderate-to-severe adverse effects [1]. Thus, there is a growing interest in sublingual administration as an effective alternative [1,2]. One of the advantages of sublingual immunotherapy (SLIT) is that, as an oral drug, it can be administered at home.…”

Sublingual Immunotherapy in the Treatment of Atopic Dermatitis: a Systematic Review Using the GRADE System

“…Three sublingual tablets have been approved in the USA: Oralair, a mixture of five northern pasture grasses; Grastek, which contains Timothy grass; and Ragwitek, which contains ragweed. Although many allergy patients are polysensitized in the USA, the possibility of a dust mite sublingual tablet becoming available, perhaps as early as 2015, could lead to a significant change in the way that many allergists prescribe AIT [13].…”

Patient selection for subcutaneous versus sublingual immunotherapy

“…Multiallergen SLIT in the United States has not been approved and there is no reimbursement code for this modality. Even so, SCIT extracts are used off-label to prepare liquid SLIT formulations by some allergists and by almost one-third of ENT physicians [9][10][11]. Care should be taken in such practices, as dual allergen liquid SLIT with two nonrelated allergens has been shown to be effective [7 && ,12], but SLIT with ten allergens mixed in one vial was not [8 && ].…”