Abstract. Multimodal approaches that combine near-infrared (NIR) and conventional imaging modalities have been shown to improve optical parameter estimation dramatically and thus represent a prevailing trend in NIR imaging. These approaches typically involve applying anatomical templates from magnetic resonance imaging/ computed tomography/ultrasound images to guide the recovery of optical parameters. However, merging these data sets using current technology requires multiple software packages, substantial expertise, significant time-commitment, and often results in unacceptably poor mesh quality for optical image reconstruction, a reality that represents a significant roadblock for translational research of multimodal NIR imaging. This work addresses these challenges directly by introducing automated digital imaging and communications in medicine image stack segmentation and a new one-click three-dimensional mesh generator optimized for multimodal NIR imaging, and combining these capabilities into a single software package (available for free download) with a streamlined workflow. Image processing time and mesh quality benchmarks were examined for four common multimodal NIR usecases (breast, brain, pancreas, and small animal) and were compared to a commercial image processing package. Applying these tools resulted in a fivefold decrease in image processing time and 62% improvement in minimum mesh quality, in the absence of extra mesh postprocessing. These capabilities represent a significant step toward enabling translational multimodal NIR research for both expert and nonexpert users in an open-source platform. © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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This article traces and explains how U.S. policy officials and IR scholars have conceived of the relationship between economics and security over the past half-century. During the interwar years, economics and security were integrated in both scholarship and statecraft. During the Cold War, scholars treated the two issues as separate areas of inquiry. U.S. policymakers integrated economics and security during the early Cold War, but by the 1970s the two components of U.S. foreign policy had drifted apart. After the Cold War, a renewed emphasis has emerged in both U.S. statecraft and IR scholarship on the integration of economics and security. Three factors explain these patterns: (1) the international distribution of material capabilities, (2) perceptions of the strategic environment, and (3) perceptions of the position of the United States in international economic competition.