To cite this version:Michaël Dauge, Michaël Gauthier, Emmanuel Piat. Modelling of a planar magnetic micropusher for biological cell manipulations.. Sensors and Actuators A: Physical , Elsevier, 2007, 138, pp.239-247. The improving of the efficiency and the automation of biological cell technologies is currently of great importance. One way is to build biological micro-factories which are able to perform complete biotechnological processes automatically. This technology requires the development of new automatic cell transport system to feed work stations in microfactories. An original magnetic cell micropusher is described in this paper. The ferromagnetic pusher which is submerged in the biological medium follows the movement of a permanent magnet located in the air. This paper focuses on the modelling of the dynamic behaviour of the micropusher according to the magnet trajectory. The generic model proposed is able to determine pusher trajectory according to the micropusher magnetic properties and the permanent magnet shape and properties. This simulation tool will permit to optimize and to study cell trajectory control in further works.Area -Micromechanics.
This paper deals with a magnet cell transport system designed to supply test and treatment modules (e.g. units of a bio-microfactory). Our cell transport system is based on magnetic micro-actuation. Cells are pushed by a ferromagnetic microparticle (diameter 200 , thickness 25 ). The motion of the microparticle is performed and controlled by an external magnetic field. In this paper, we present the modelling of the pusher behavior. Our model is composed of a magnetic block (internal magnetic micropusher behaviour), strain block (torque and force applied on the micropusher by the magnet) and dynamic block (dynamic micropusher behaviour). This paper also presents some results like computation of static equilibrium position, comparison with experimental results and size influence study comparison.
To cite this version:Michaël Dauge, Michaël Gauthier, Emmanuel Piat. Abstract -The improving of the efficiency and the automation of biological cell technologies is a current high stake. One way is to build biological micro-factories which are able to perform a complete biotechnological processes automatically. This technology requires the development of new automatic cell transport system to feed work stations in microfactories. An original magnetic cell micropusher is described in this paper. The ferromagnetic pusher which is submerged in the biological medium follows the movement of a permanent magnet located in the air. This paper focuses on the modelling of the dynamic behaviour of the micropusher in function of the magnet trajectory. The generic model proposed is able to determine pusher trajectory according to the micropusher magnetic properties and the permanent magnet shape and properties. This simulation tool will allow to optimize and to study cell trajectory control in further works.
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