One year after treatment, characterized chondrocyte implantation was associated with a tissue regenerate that was superior to that after microfracture. Short-term clinical outcome was similar for both treatments. The superior structural outcome may result in improved long-term clinical benefit with characterized chondrocyte implantation. Long-term follow-up is needed to confirm these findings.

No abstract

The occurrence and distribution of SP nerves inside the infrapatellar fat pad suggest a nociceptive function and a neurohistological role in anterior knee pain syndrome. The data support the hypothesis that a neurogenous infection of the infrapatellar fat pad could contribute to anterior knee pain syndrome.

This study compares the effects of two different techniques of medial patellofemoral ligament (MPFL) reconstruction, and proximal soft tissue realignment on patellar stabilization against lateral dislocation. Eight human cadaver knee specimens with no radiological pathomorpholgy on a straight lateral view, contributing to patellofemoral instability, were mounted in a kinematic knee simulator and isokinetic extension was simulated. Patellar kinematics were measured with an ultrasound positioning system (zebris) while a 100 N laterally directed force was applied to the patella. The kinematics were compared with intact knee conditions under MPFL deficient conditions, as well as following dynamic reconstruction of the MPFL using a distal transfer of the semitendinosus tendon, following static reconstruction by a semitendinosus autograft, and following proximal soft tissue realignment of the patella (Insall procedure). Dynamic reconstruction of the MPFL resulted in no significant alteration (P = 0.16) of patellar kinematics. Static reconstruction of the MPFL significantly medialized (P < 0.01) the patellar movement without, but restored intact knee kinematics under the laterally directed force. In contrast, following proximal soft tissue realignment, the patellar movement was constantly medialized and internally tilted (P = 0.04). Dynamic and static reconstruction of the MPFL create sufficient stabilization of the patella. Following proximal soft tissue realignment, the patellar position was over-medialized relative to intact knee conditions, which could lead to an overuse of the medial retropatellar cartilage.

This biomechanical study was performed to measure tissue pressure in the infrapatellar fat pad and the volume changes of the anterior knee compartment during knee flexion-extension motion. Knee motion from 120 degrees of flexion to full extension was simulated on ten fresh frozen human knee specimens (six from males, four from females, average age 44 years) using a hydraulic kinematic simulator (30, 40, and 50 Nm extension moment). Infrapatellar tissue pressure was measured using a closed cell sensor. Infrapatellar volume change in the anterior knee compartment was evaluated subsequent to removal of the fat pad using a water-filled bladder. We found a significant increase of the infrapatellar tissue pressure during knee flexion, at flexion angles of <20 degrees and >100 degrees . The average tissue pressure ranged from 343 (+/-223) mbar at 0 degrees to 60 (+/-64) mbar at 60 degrees of flexion. The smallest volume in the anterior knee compartment was measured at full extension and 120 degrees of flexion, whereas the maximum volume was observed at 50 degrees of flexion. In conclusion, the data suggest a biomechanical function of the infrapatellar fat pad at flexion angles of <20 degrees and >100 degrees , which suggests a role of the infrapatellar fat pad in stabilizing the patella in the extremes of knee motion.

The infrapatellar fat pad may have a biomechanical function and may play a role in anterior knee pain syndrome.

No abstract

The purpose of this study was to evaluate the biomechanical properties of commonly used autogenous transplants for the surgical stabilization of chronic lateral ankle instability. We dissected the transplants (peroneus longus, peroneus brevis, Achilles and plantaris tendon, periosteal flap, fascia, corium) and the anterior talofibular ligament from 13 fresh anatomic specimens. After laser-assisted measurement of the transplant diameter, we assessed their biomechanical properties with a universal testing device. Biomechanical stability of the peroneus longus, peroneus brevis, and Achilles tendons was significantly higher than the other transplants. The stability parameters of the periosteal flap were in the range of the anterior talofibular ligament but inferior to the tendons. The application of a transplant with low biomechanical stability, such as the periostal flap, requires more postoperative immobilization as in a strong orthosis or cast.