The objective of this study was to describe the reference values of cranial measurements of capybaras, correlating the ocular orbit with the nasolacrimal duct. The documentation of its results can contribute to standardizing characteristics of anatomical normality and favouring the correct diagnosis and treatment of changes. The capybara carcasses, maintained by freezing, were distributed in two groups (G) designated GA (n = 12) adult animals (A) and GY (n = 13) for young animals (Y). All subjects underwent dacryocystography examination by computed tomography (CT) and cranial measurements. Descriptive analyses of cranial and nasolacrimal duct measurements and statistical analysis of the Pearson correlation with the variable weight were performed. In GA, there was no correlation between the nasolacrimal and cranial duct measurements. However, in the GY, a correlation was verified with facial length (r = .6233), facial width (r = .5771), cranial height (r = .6981), cranial length (r = .7116), total right length (r = .7517) and left length (r = .7999). Thus, in the young animals, cranial length measurements were strongly correlated with nasolacrimal duct lengths. However, this biological behaviour was not observed in adults, demonstrating stability in development. The capybara's ocular orbit was found to be circular and incomplete, with developed zygomatic process of the maxilla. CT dacryocystography is indicated to evaluate the nasolacrimal canal pathway in capybaras, emphasizing the importance of normal anatomical study to aid in treating animals affected by diseases.

Simple SummaryProgressive retinal atrophy (PRA) in English cocker spaniels (ECSs) is associated with progressive rod–cone degeneration (prcd-PRA), an inherited autosomal recessive disease caused by the c.5G>A mutation in the progressive rod–cone degeneration (PRCD) gene. Data regarding the prevalence of the mutated allele are scarce in the global literature, and there is no study evaluating this frequency in Brazil. Therefore, the aim of this study was to evaluate the allele frequency of the c.5G>A mutation in the PRCD gene responsible for progressive retinal atrophy (prcd-PRA) in ECS dogs.AbstractProgressive retinal atrophy (PRA) due to the c.5G>A mutation in the progressive rod–cone degeneration (PRCD) gene is an important genetic disease in English cocker spaniel (ECS) dogs. Because the prevalence of this disease has not been verified in Brazil, this study aimed to evaluate the allele frequency of the c.5G>A mutation in the PRCD gene. Purified DNA from 220 ECS dogs was used for genotyping, of which 131 were registered from 18 different kennels and 89 were unregistered. A clinical eye examination was performed in 28 of the genotyped animals; 10 were homozygous mutants. DNA fragments containing the mutation region were amplified by PCR and subjected to direct genomic sequencing. The prcd-PRA allele frequency was 25.5%. Among the registered dogs, the allele frequency was 14.9%; among the dogs with no history of registration, the allele frequency was 41%. Visual impairment was observed in 80% (8/10) of the homozygous mutant animals that underwent clinical eye examination. The high mutation frequency found in this study emphasizes the importance of genotyping ECSs as an early diagnostic test, especially as part of an informed breeding program, to avoid clinical cases of PRA.

Cláudia Valéria Seullner Brandão 5 MERLINI, N. B.; GUBERMAN, U. C.; GANDOLFI, M. G.; SOUZA, V. L. de; RODAS, N. R.; RANZANI, J. J. T.; BRAN-DÃO, C. V. S. Estudo retrospectivo de 71 casos de protrusão da glândula da terceira pálpebra (2009)(2010)(2011)(2012)(2013). Arq. Ciênc. Vet. Zool. UNIPAR, Umuarama, v. 17, n. 3, p. 177-180, jul./set. 2014. RESUMO:Objetivou-se com esse estudo avaliar a incidência de protrusão da glândula da terceira pálpebra e correlacionar as características de raça e sexo com a lateralidade da alteração. Para isso, foram analisadas 3.151 fichas clínicas atendidas setor de oftalmologia veterinária da Universidade Estadual de São Paulo (UNESP) no período de 2009 a 2013, avaliando-se dados de incidência e lateralidade da afecção, além de idade, sexo e raça dos animais acometidos. Realizou-se a análise estatística de frequência e calculou-se o coeficiente de correlação de Spearman, considerando o nível de significância de 5%. Foram diagnosticados, no total, 71 casos de protrusão da glândula da terceira pálpebra em cães, correspondendo a 2,43% (71/2.916) da casuística de atendimento oftalmológico nesta espécie, porém não foi observado nenhum caso em gatos. Obteve-se uma maior frequência (58%, 41/71) em cães com idade inferior a 12 meses, sendo as raças mais acometidas: Lhasa Apso (24%, 17/71), Sem Raça Definida (20%, 14/71) e Beagle (14%, 10/71). Em 72% (44/71) dos casos a afecção se manifestou unilateral e 55% (39/71) dos animais eram fêmeas. Não houve correlação entre o sexo e a raça com a lateralidade da protrusão (p > 0,05). Com base no levantamento de dados realizados nesta instituição, conclui-se que a incidência da afecção é baixa em cães e rara em gatos, além de que não há influência do sexo e da raça com relação ao lado acometido pela alteração. PALAVRAS-CHAVE: Cães. Cherry eyes. Gatos. Membrana nictitante. Prolapso. RETROSPECTIVE STUDY OF 71 CASES OF PROLAPSED THIRD EYELID GLAND (2009-2013)ABSTRACT: This paper aims to analyze the incidence of prolapsed third eyelid gland and correlate the breed and gender characteristics to the laterality of the alteration. In order to do this, three thousand one hundred and fifty-one (3151) medical records were analyzed at the Department of veterinary ophthalmology from the State University of São Paulo (UNESP) from 2009 to 2013, considering data such as the incidence and laterality of the disease, as well as age, gender and breed of affected animals. A frequency statistical analysis was performed and the Spearman correlation coefficient was calculated by taking the significance level of 5%. The prolapse of the third eyelid gland was diagnosed in 71 cases in dogs, which corresponds to 2.43% (71/2916) of the cases cared for in the ophthalmological assistance in this specie; however, no cases were observed in cats. Dogs younger than 12 months of age presented a higher frequency, (58%, 41/71). The breeds most affected were Lhasa Apso (24%, 17/71); Mongrel (20%, 14/71); and Beagle (14%, 10/71). The prolapse was unilateral in 72% (44/71) of the cases, and...

RESUMOObjetivou-se com este trabalho determinar o poder dióptrico da lente intraocular (LIO) em miniporco e as dimensões do bulbo do olho. Foram utilizados 17 miniporcos, sadios, adultos, machos e fêmeas, com peso médio de 70kg. porte e da propensão ao ganho de peso, sendo cada vez mais proposto o uso do miniporco. Este possui, como vantagens, menor tamanho, consequente facilidade no manuseio, redução no dispêndio com alimentação, criação e, adicionalmente, possibilita estudos de longa duração (Kohn, 2012).

The objective in this study was to evaluate the clinic effect of applying allogenic platelet-rich plasma (PRP) heated or not, for treating cornea ulcers, including the dosage of PDGF-BB in the cornea. The ulcers were induced, standardizing the left eye from 81 rats (Ratus norvegicus, albinus variety), assigned randomly into three groups (N=27): control group (CG) which did not receive any topic treatment; heated PRP group (GA) and PRP group (GP), which received topical treatment every eight hours for five days. Each group underwent evaluation at 24 hours (M1), three days (M3) and five days (M5). The clinical exam evaluated the opacity, vascularization and corneal repair. The corneal PDGF-BB was dosed through the ELISA method. The corneal opacity was decreased in PRP-treated animals (GA and GP) and corneal repair time reduced when compared to CG at M1 and M5. Furthermore, GP showed greater vascularization at M3 compared to M1. Applied allogenic PRP eye drops, heated or not, speed up corneal healing, and reduce corneal repair time. However, the corneal PDGF concentration was not altered in any of the treatments.

Objective:The aims of this study were to compare the central corneal thickness (CCT) measured by an ultrasonic pachymeter (SP-100, Tomey, Japão) versus the Galilei G6™ (Ziemer Ophthalmics System AG, Port, Switzerland) and to compare the simulated keratometry (SimK) measured by an autokeratometer (KM 500 Nidek) versus the Galilei G6™.Animal studied: Eighteen mixed-breed cats, 10 males, and eight females, aged between 18 and 48 months, were evaluated (n = 36 eyes). Procedure(S):The cats were manually restrained using a blanket. The operator held the autokeratometer close to the eye and measured the SimK. Next, one anesthetic eye drop was applied; the operator lightly touched the corneal using the ultrasound pachymeter and measured the CCT. At another moment, the cats were sedated using meperidine and xylazine and then evaluated using the Galilei.Student's t-test was employed to perform the statistical analyzes.Results: Considering the CCT, the ultrasound pachymeter provided mean ± SD of 623.03 ± 48.17 μm and the Galilei 617.34 ± 53.38 μm. The autokeratometer produced a SimK of 38.20 ± 0.84D (8.84 ± 0.20 mm) and the Galilei 38.37 ± 0.83D