Aims:This study evaluated the biocompatibility of the Indian Portland cement with potential for use in dentistry.Materials and Methods:This study was performed in Swiss albino mice, by implanting the Indian Portland cement pellets subcutaneously. After 1, 3, and 6 weeks the tissue specimens were prepared for histological examination.Results:The histological analysis showed moderate to severe inflammation at 1 week. The inflammation gradually decreased by 6 weeks, with most of the specimens showing the absence of inflammatory reaction.Conclusions:According to these experimental conditions, the tested Indian Portland cement was biocompatible.
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