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This paper presents a low-voltage nano-power multiple-input operational transconductance amplifier (MI-OTA) with high linearity performance and increased input voltage swing. The enhanced performances are achieved thanks to employing several techniques as the bulk-driven, source-degeneration, self-cascode and negative conductance along with the concept of the input signal attenuation formed by multiple-input MOS transistor. The MI-OTA is widely tunable that serves for biological signals processing. A 3 rd -order Butterworth band-pass filter (BPF) for electrocardiogram (ECG) signal processing with 55.8 dB dynamic rang is presented. The MI-OTA circuit is designed for 0.5V voltage supply and offers a 0.22% total harmonic distortion (THD) for 0.2V pp input signal with total power consumption of 13.4nW. Extensive simulation results including Monte Carlo analysis and process, voltage, temperature (PVT) corners using the 0.18µm CMOS technology from TSMC confirm the characteristics of the proposed MI-OTA and the filter.INDEX TERMS Operational transconductance amplifier (OTA), bulk-driven MOS transistor, multiple-input OTA, high-order filters.

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Summary This paper presents a two‐stage bulk‐driven operational transconductance amplifier operating in weak‐inversion region. The proposed amplifier is upgraded using recycling structure, current shunt technique, positive feedback source degeneration and indirect frequency compensation feedback to enhance transconductance under a reasonable stability. Combining these approaches leads to an ultra‐low‐power high performance amplifier without increasing power dissipation compared to the conventional one. Simulation results in 0.13‐µm complementary metal–oxide–semiconductor technology show the proposed structure achieves a 63‐dB DC gain at 0.25‐V supply voltage with just 20‐nW power dissipation. Copyright © 2016 John Wiley & Sons, Ltd.