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In this study, fully developed mixed convective heat transfer of a Newtonian fluid in an open-ended vertical parallel plate microchannel is analytically investigated by taking the velocity slip and the temperature jump at the wall into account. The effects of the mixed convection parameter, Gr/Re, the Knudsen number, Kn, and the ratio of wall temperature difference, rT, on the microchannel hydrodynamic and thermal behaviors are determined. Finally, a Nu=f(Gr∕Re,Kn,rT) expression is developed.

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