Introduction Minimal research has been conducted examining the relationship of positive psychology variables with quality of life (QOL) for individuals with bleeding disorders. While many individuals manage their bleeding disorders well, some are at higher risk of developing psychosocial complications due to the daily stressors of managing illness‐related symptoms. Aim The purpose of this study is to better understand the relationships between two positive psychology variables, self‐compassion and hope and QOL (overall, psychosocial and physical) among individuals diagnosed with bleeding disorders. Methods Participants completed a survey identifying demographic information as well as rating scales of self‐compassion, hope and quality of life. We conducted Pearson correlational and standard multiple regression analyses to explore the bivariate and linear relationships between the aforementioned variables in a sample of 86 patients with bleeding disorders between the ages of 15 and 65. Results Self‐compassion and hope were significantly related to QOL. Together, self‐compassion and hope were predictive of overall QOL, psychosocial QOL and physical QOL. However, hope was the only individual predictor of all three QOL dimensions. Conclusion Due to the significant relationships found between self‐compassion, hope and QOL in this sample, it may be beneficial to incorporate positive psychology factors into the treatment of those diagnosed with bleeding disorders, especially those at higher risk for decreased QOL.

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