Background. Endodontic sealers are essential for sealing gutta-percha to the dentin walls. They help to ensure that the canal remains free of microorganisms which might lead to infection. In order to perform their intended function, the sealers should properly adhere to the dentin walls and remain insoluble when set in the canal. Objectives. The purpose of this study was to evaluate the bond strength and solubility of a novel polydimethylsiloxane-gutta-percha calcium silicate-containing root canal sealer (GuttaFlow ® bioseal) and compare it with the zinc oxide and eugenol sealer (Zical ®). Material and methods. The endodontic sealers used in this study were GuttaFlow bioseal and Zical. The bond strength was assessed using push-out bond strength test in 3 root segments: coronal, middle and apical. The solubility was tested according to the American National Standards Institute / American Dental Association (ANSI/ADA) specification No. 57 at 3 different time intervals: 1, 7 and 14 days. Results. The push-out bond strength in all root segments was significantly higher in Zical compared to GuttaFlow bioseal. The solubility was significantly higher on day 1 and 7 in Zical compared to GuttaFlow bioseal, and on day 14, the difference between them was not significant. Conclusions. Within the limitations of this study, the endodontic sealer GuttaFlow bioseal showed low bond strength values compared to Zical. The solubility of the set GuttaFlow bioseal and Zical were both within the recommended ANSI/ADA levels.
BACKGROUND: Polymethylmethacrylate (PMMA) is commonly used for dental appliances but has several shortcomings that could benefit from improvement with the use of nanoparticles (NPs). AIM: The purpose of this study was to modify PMMA with three different antimicrobial NPs; Graphene oxide nanosheets (nGO), Titanium dioxide NPs (TiO2 NPs) and curcumin (CUR)-loaded graphene oxide nanosheets alone, and in combination and assess the flexural strength and hardness of the different groups. MATERIALS AND METHODS: The material used in this study was chemically cured PMMA that was modified with nGO, TiO2 NPs and GOCUR alone and in combination to give 6 groups; Group A: PMMA, Group B: PMMA with nGO, Group C: PMMA with TiO2 NPs, Group D: PMMA with TiO2 and GO NPs, Group E: PMMA with GOCUR, and Group F: PMMA with TiO2 NP, and GOCUR. The Six groups were tested for flexural strength and hardness. Statistical analysis was and data were expressed as means and standard deviation. Data was explored for normality using the Kolmogorov-Smirnov test of normality. The ANOVA test was used to compare between groups, followed by Bonferroni’s post hoc test for pairwise comparison. The significance level was set at p ≤ 0.05. RESULTS: The highest flexural strength was recorded in Group C (52.26 ± 5.48 MPa) and the lowest value was in Group A (24.94 ± 5.37 MPa). The highest hardness was recorded in Group F (23.29 ± 0.8 HV) and the lowest value was in Group A (15.88 ± 1.02 HV). CONCLUSION: The modification of PMMA with NPs with proven antimicrobial activity can increase the flexural strength and hardness of the material. GO, TiO2 and, GOCUR NPs were each used alone and in different combinations, and all the groups displayed higher flexural strength and hardness than the unmodified PMMA.
Background. Root-end filling materials are used in surgical endodontic treatment to seal the teeth periapically. Ideally, these materials should prevent bacterial leakage by tightly sealing the canal, be biocompatible with the periapical tissues, and preferably stimulate the regeneration of dentin, contributing to the success of treatment.Objectives. The purpose of this study was to evaluate and compare the biocompatibility of the Gutta-Flow ® Bioseal cement in relation to MTA Angelus ® and Zical ® after implantation into the subcutaneous tissue of rats. Material and methods.Eighteen male albino rats were used in the study. Four polyethylene tubes were implanted in the backs of the rats (3 tubes containing the test materials and 1 empty tube as a control). Nine animals were sacrificed at each interval of 7 and 30 days, and the implants were removed with the surrounding tissue. The samples were evaluated for stromal inflammatory response, fibrous tissue formation, vascular reactivity, and the presence of multinucleated giant cells (MNGCs).Results. On day 7, the capsules in all subgroups revealed moderate to severe inflammatory reactions with the presence of inflammatory cells, multiple irregular collagen fibers, dilated blood vessels, and MNGCs. However, on day 30, tissue organization was more evident with a reduction in the inflammatory response. In this time interval, the tissue in contact with GuttaFlow Bioseal showed progressive healing with a wellformed fibrous capsule. Conversely, the tissue close to MTA Angelus revealed a fibrous capsule of limited organization with mild pericapsular fibrosis and vascular congestion. Zical showed a mild to moderate persistent inflammatory reaction and vascular reactivity.Conclusions. The 3 cements demonstrated more severe irritation at the beginning that became milder with time. GuttaFlow Bioseal yielded better tissue organization than MTA Angelus and Zical. Thus, these findings strongly suggest that GuttaFlow Bioseal is a promising material for root-end filling.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.