The fluorescent pH-responsive mesoporous silica nanoparticles (P@BMMs) were prepared, in which, the (2-[3-(triethoxysilyl) propyl]-1H-Benz [de]isoquinoline-1, 3(2H)-dione) -poly(acrylic acid) (PID-PAA) shell was covalently anchored onto the vinylmodified surface of the bimodal mesoporous materials (BMMs) core via one-step or two-step process. Their structural features were analyzed by XRD, SEM, TEM, TG, and SAXS, and the results showed that P@BMMs possessed typical fractal features from structural irregularity to surface roughness. Ibuprofen as a model drug was loaded into the mesopore channels of BMMs cores, particularly, the drug-releasing performances from P@BMMs carriers were pH-dependent. Meanwhile, the photoluminescent emission spectra and the fluorescent decay profiles presented that the hybrid P@BMMs with strong fluorescent intensity at 395 nm and 450 nm and longer decay lifetimes (such as 3.53 and 18.86 ns for P@BMMs-I-10) is a promising drug carrier, which can be used in potential applications for controlled drug delivery.[a] T.
In order to understand the growth behaviors of the aluminosilicate species in the initial hydrothermal process and thereafter synthesis of clinoptilolites with high purity, the physicochemical characteristics of the aluminosilicate nanoparticles were elucidated by small angle X-ray scattering (SAXS) and X-ray diffraction (XRD) patterns, scanning electron microscopy (SEM) images, Ultra-Violet Raman (UV-Raman) and Fourier transform infrared (FT-IR) spectra. The results demonstrated that the aluminosilicate nanoparticles presented the first decreased surface fractal (D s ) values and then an increased D s values in the initial reaction time of before 120 h. After that, the fractal transformations from D s to mass fractal (D m ) occurred with the extensions of reaction time (120-144 h), but the decreased D m values appeared after 144 h. Therefore, their growth mechanisms from uniform dispersions to aggregation, and even assembly were proposed.
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