For the medical industry, there are problems such as poor sharing of medical data, tampering, and leakage of private data. In view of these problems, a blockchain-based electronic medical record access control research scheme based on the role-based access control model is proposed in this article. First, the appropriate access control strategy is adopted to solve the leakage problem of the user’s medical privacy information during the access process. Then, the information entropy technology is used to quantify the medical data, so that the medical data can be effectively and maximally utilized. Using the distributed general ledger characteristics of blockchain and its inherent security attributes, data islands can be eliminated, data sharing among medical systems can be promoted, access records can be prevented from being tampered with, and medical research and precise medical treatment can be better supported. Through this research, not only can user’s medical privacy information protection be realized during the service process but also patients can manage their own medical data autonomously, which is beneficial to privacy protection under the medical data sharing.
The role of excision repair cross-complementation group 6-like (ERCC6L) has been reported in several cancers, but little is known about its expression and function in laryngeal squamous cell carcinoma (LSCC). In this study, the expression of ERCC6L in LSCC was determined by immunohistochemistry and its correlation with prognostic factors was analyzed. Furthermore, cytological functional validation elucidated the role and underlying mechanisms of ERCC6L dysregulation in LSCC. Our data revealed that ERCC6L expression was elevated in LSCC and it’s correlated with TNM stage. In addition, ERCC6L knockdown LSCC cells showed decreased proliferation and migration, increased apoptosis, and reactive oxygen species (ROS). Mechanically, overexpression of ERCC6L promoted nuclear translocation of FOXM1 to facilitate direct binding to the KIF4A promoter and upregulated KIF4A expression. Furthermore, KIF4A knockdown attenuated the role of ERCC6L overexpression in promoting proliferation, migration, and tumorigenesis of LSCC cells. In summary, ERCC6L promoted the binding of FOXM1 and KIF4A in LSCC cells to drive their progression, which may be a promising target for precision therapy in this disease.
The construction of an international Chinese teaching platform in a smart environment is the key to realize smart education and promote the modern development of international Chinese education. The traditional teaching resource platform has many problems, and it is difficult to meet the intellectual needs of learners. Based on the needs of education and teaching reform under the background of new liberal arts, the article deeply analyzes the implementation path of smart environment and international Chinese teaching resources and platform construction, constructs a system framework for smart resource platform construction, and finally discusses the development trend of international Chinese teaching in a smart environment. Discussions were conducted in order to provide a reference for the intelligent upgrading and transformation of international Chinese education.
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