The increased raltegravir exposure observed with once-weekly rifapentine was safe and tolerable. Once-weekly rifapentine can be used with raltegravir to treat latent tuberculosis infection in patients who are infected with HIV.
BACKGROUND: A number of individual high-performance liquid chromatography (HPLC) procedures exist for the analysis of maltol, theobromine, ethyl maltol, catechin, vanillic acid, caffeine, vanillin, epicatechin, and ethyl vanillin. A single procedure utilizing simple sample preparation and less sophisticated equipment would be advantageous for the analysis of different sample types containing these compounds.
ABSTRA ABSTRA ABSTRA ABSTRA ABSTRACT CT CT CT CT: A new : A new : A new : A new : A new, all aqueous high-per , all aqueous high-per , all aqueous high-per , all aqueous high-per , all aqueous high-perfor for for for formance liquid chr mance liquid chr mance liquid chr mance liquid chr mance liquid chromatogr omatogr omatogr omatogr omatography (HPL aphy (HPL aphy (HPL aphy (HPL aphy (HPLC) pr C) pr C) pr C) pr C) procedur ocedur ocedur ocedur ocedure for the deter e for the deter e for the deter e for the deter e for the determinamina-mina-minamination of 5-hydroxymethylfurfural (HMF) in honey and other sugar-containing materials was developed without tion of 5-hydroxymethylfurfural (HMF) in honey and other sugar-containing materials was developed without tion of 5-hydroxymethylfurfural (HMF) in honey and other sugar-containing materials was developed without tion of 5-hydroxymethylfurfural (HMF) in honey and other sugar-containing materials was developed without tion of 5-hydroxymethylfurfural (HMF) in honey and other sugar-containing materials was developed without harmful chemicals. The method involved dilution of the sample in water and the analysis of the diluent using an harmful chemicals. The method involved dilution of the sample in water and the analysis of the diluent using an harmful chemicals. The method involved dilution of the sample in water and the analysis of the diluent using an harmful chemicals. The method involved dilution of the sample in water and the analysis of the diluent using an harmful chemicals. The method involved dilution of the sample in water and the analysis of the diluent using an HPLC system equipped with an absorbance detector and a 30-mm sulfonated poly(styrene-divinylbenzene) HPLC system equipped with an absorbance detector and a 30-mm sulfonated poly(styrene-divinylbenzene) HPLC system equipped with an absorbance detector and a 30-mm sulfonated poly(styrene-divinylbenzene) HPLC system equipped with an absorbance detector and a 30-mm sulfonated poly(styrene-divinylbenzene) HPLC system equipped with an absorbance detector and a 30-mm sulfonated poly(styrene-divinylbenzene) cation ex cation ex cation ex cation ex cation exchange column. change column. change column. change column. change column. W W W W Water was used as the mobile phase at a high flo ater was used as the mobile phase at a high flo ater was used as the mobile phase at a high flo ater was used as the mobile phase at a high flo ater was used as the mobile phase at a high flow r w r w r w r w rate of 2.00 mL/min ate of 2.00 mL/min ate of 2.00 mL/min ate of 2.00 mL/min ate of 2.00 mL/min . . .. . U U U U Using this high sing this high sing this high sing this high sing this high flow rate in conjunction with a column heater set at 55 °C, HMF eluted in less than 4 min. Overall precision was flow rate in conjunction with a column heater set at 55 °C, HMF eluted in less than 4 min. Overall precision was flow rate in conjunction with a column heater set at 55 °C, HMF eluted in less than 4 min. Overall precision w...
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