We propose a new shape-based segmentation approach using the statistical shape prior and level sets method. The segmentation depends on the image information and shape prior. Training shapes are grouped to form a probabilistic model. The shape model is embedded into the image domain taking in consideration the evolution of a contour represented by a level set function. The evolution of the front gathers information from the image intensities and shape prior. The segmentation approach is applied in segmenting the vertebral bodies in CT images. Our results shows that the technique is accurate and robust compared with the other alternative in the literature.Index Terms-Simultaneous segmentation and registration, vertebral body (VB).
Osteoporosis is a bone disease characterized by a reduction in bone mass, resulting in an increased risk of fractures. To diagnose the osteoporosis accurately, bone mineral density (BMD) measurements and fracture analysis (FA) of the Vertebral bodies (VBs) are required. In this paper, we propose a robust and 3D shape based method to segment VBs in clinical computed tomography (CT) images in order to make BMD measurements and FA accurately. In this experiment, image appearance and shape information of VBs are used. In the training step, 3D shape information is obtained from a set of data sets. Then, we estimate the shape variations using a distance probabilistic model which approximates the marginal densities of the VB and background in the variability region. In the segmentation step, the Matched filter is used to detect the VB region automatically. We align the detected volume with 3D shape prior in order to be used in distance probabilistic model. Then, the graph cuts method which integrates the linear combination of Gaussians (LCG), Markov Gibbs Random Field (MGRF), and distance probabilistic model obtained from 3D shape prior is used.
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