Objective: To investigate the macronutrient content of human milk during the first 28 days of lactation of mothers who delivered preterm infants, and to compare preterm to term milk. Methods: A prospective and longitudinal study of mothers at various stages of lactation was conducted in the Amiens-Picardie University Hospital (France). Fat, true protein, carbohydrate and energy contents were estimated in human milk collected from each participant. Results: Macronutrients in human milk were: fat (g/100 mL), 3.36±1.01; true protein (g/100 mL), 1.34±0.61; carbohydrate (g/ 100 mL), 7.23±0.68; energy (kcal/100 mL), 72.97±9.21 for extremely preterm human milk; fat (g/100 mL), 3.47±1.14; true protein (g/100 mL) 1.32±0.63; carbohydrate g/100 mL), 7.28±1.10; energy (kcal/100 mL), 76.18±12.84 for very preterm human milk; fat (g/100 mL), 3.48±0.87; true protein (g/100 mL), 1.26±0.46
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