Cases of pregnant women who are HIV-AIDS positive have increased from 2017-2020. More than 90% of HIV-infected infants are infected by HIV-positive mothers. Transmission can occur during pregnancy, during delivery and during breastfeeding. This service aims to increase the knowledge of pregnant women about preventing HIV transmission from mother to child. The method used is to provide health promotion to 15 pregnant women. Health promotion was delivered with the theme of preventing HIV transmission from mother to child through booklets. The results of the counseling showed that there was a significant increase in the understanding of pregnant women about preventing HIV transmission from mother to child from 43.5% to 80.25%. Based on these results, it is expected that the knowledge of pregnant women about preventing HIV transmission from mother to child will increase so that it can affect the attitude of pregnant women to the problem and ultimately be able to reduce morbidity and mortality in pregnant women.Keywords: pregnant women, health promotion, prevention of mother-to-child transmission of HIV (PPIA)                                                                                                                                              ABSTRAK  Kasus ibu hamil yang positif HIV-AIDS meningkat dari tahun 2017-2020. Lebih dari 90% bayi terinfeksi HIV tertular dari ibu HIV positif. Penularan tersebut dapat terjadi pada masa kehamilan, saat persalinan dan selama menyusui. Pengabdian ini bertujuan untuk meningkatkan pengetahuan ibu hamil tentang pencegahan penularan HIV dari ibu ke anak. Metode yang digunakan adalah memberikan promosi kesehatan kepada 15 ibu hamil. Promosi kesehatan disampaikan dengan tema pencegahan penularan HIV dari ibu ke anak melalui media booklet. Hasil penyuluhan menunjukkan terdapat peningkatan yang signifikan pemahaman ibu hamil tentang pencegahan penularan HIV dari ibu ke anak  43,5% menjadi 80,25%. Berdasarkan hasil ini diharapkan pengetahuan ibu hamil tentang pencegahan penularan HIV dari ibu ke anak semakin meningkat sehingga dapat mempengaruhi sikap ibu hamil terhadap masalah tersebut dan pada akhirnya mampu menurunkan angka kesakitan dan kematian pada ibu hamil   Kata kunci: ibu hamil, promosi kesehatan, pencegahan penularan HIV dari ibu ke anak (PPIA)

The launch of breast milk on postpartum mothers should be treated appropriately to make the exclusive breast milk work smoothly. The survey result in Gampengrejo’s community health center in April 2019 was obtained 9 out of 14 postpartum mothers (64.28%) experiencing breast milk flow problems. Postpartum mothers consuming boiled katuk and kelor leaves can smooth the flow of breast milk. Many problems have been spent on the post-partum mothers on day 1 up to day 7. The purpose of this study is to determine the influence of the combination of boiled katuk and kelor leaf. The design of the research used is an experimental study with a pre-experimental design using pre-test and post-test design. The population is the mother of the postpartum on day 1 through day7 in Gampengrejo’s community health center Kediri. The sampling technique uses a simple random sampling technique and it is obtained 16 samples. The samples are given the treatment of a combination of boiled katuk and kelor leaves. The research instrument used is an observation sheet. Research results were analyzed using the Wilcoxon test. Based on the result, it shows almost all respondents breast milk that was 13 people (81.3) come out smoothly after being administered a combination of boiled katuk and kelor leaf. Based on the results of the analysis obtained ρ value 0.000 < 0.05 indicating the influence of the breast milk flow between before and after administering the combination of boiled katuk and kelor leaf. The medical staff is expected to provide information about the benefits of the combination of boiled katuk and kelor leaf for the postpartum mothers.

Anemia is a medical condition where hemoglobin levels are less than normal. Normal levels of hemoglobin differ in men and women. For men, anemia is usually defined as a hemoglobin level of less than 13.5 grams / 100 ml and in women a hemoglobin of less than 12.0 grams / 100ml. From the results of a preliminary study conducted at SMAN 5 Kediri in 2019, the results of 10 students interviewed and examination of Hb levels found that 6 (60%) students were anemic. The contributing factor is the lack of iron intake that is absorbed by the body. The purpose of this study was to determine the effect of consumption of dragon fruit (Hylocereus) on hemoglobin levels in class X students with anemia at SMAN 5 Kediri in 2019.The research design used was a pre-experimental study. The population studied was all class X students with anemia at SMAN 5 Kediri in 2019 with an accidental sampling technique obtained by a sample of 15 people. The instrument used was an observation sheet, Β-Hemoglobin hemoque, dragon fruit (Hylocereus). The research results were analyzed using Paired Sample T Test statistics Based on the results of statistical tests using the Paired Sample T Test, P value = 0,000 <α 0.05, which means that there is an influence of consumption of dragon fruit (Hylocereus) on hemoglobin in female students with anemia in SMAN 5 Kediri in 2019. The administration of dragon fruit is expected to increase hemoglobin levels in female students with anemia in SMAN 5 Kediri and maintain the intake of food consumed daily, especially by taking into account the types of nutrients including iron so that the incidence of anemia is resolved and the level of health level increases.

: Rehydration therapy aims to replace the volume of circulating tissue perfusion due to hyperosmolarity in crisis hyperglycemia patients. The administration of fluid therapy to patients with crisis hyperglycemia can trigger cerebral edema due to the mechanism of decreased osmolarity in cerebral tissue. Efforts to monitor the emergence of cerabral edema with MAE monitoring. MAE is an indicator of CPP if there is a drastic increase in MAP which will result in an increase in CPP and increase the risk of cerebral edema. This study aims to determine the difference in MAP in hyperglycemic crisis patients with fluid rehydration therapy from the first minute of administration to the last minute of administration by accumulating the amount of fluid given in that time period. A retrospective comparative category research design. The study sample consisted of 28 respondents. Based on data analysis using repeated anova, there was a difference in MAP in hyperglycemic crisis patients who received fluid rehydration therapy from the lowest amount to the highest number during therapy. Changes in the value of MAP in this study for all the amount of therapy in the normal range starting from the MAP before the therapy approaching the less or minimum value until MAP at the end of therapy at the maximum limit of the normal value of MAP. This indicates that the administration of therapy in this study will increase the amount of body fluid volume and increase in MAP without causing signs of cerebral edema.                                                     Keyword : Rehydration Therapy, MAP (Mean Arterial Pressure), hyperglycemia crisisAbstrak : Terapi rehidrasi bertujuan untuk mengganti volume sirkulasi perfusi jaringan akibat adanya hiperosmolaritas pada pasien hiperglikemia krisis.  Pemberian terapi cairan pada pasien hiperglikemia krisis bisa memicu terjadinya edema cerebral akibat mekanisme penurunan osmolaritas pada jaringan cerebral. Upaya monitoring munculnya edema cerabral dengan pematauan MAE. MAE merupakan salah satu indikator terhadap CPP apabila di dapatkan adanya peningkatan MAP yang drastis akan berakibat peningkatan CPP dan meningkatkan resiko edema cerebral. Penelitian ini bertujuan mengetahui perbedaan MAP pada pasien krisis hiperglikemia dengan terapi rehidrasi cairan  mulai dari menit pertama pemberian sampai menit terakhir pemberian dengan mengakumulasi jumlah cairan yang diberikan pada periode waktu tersebut. Desain penelitian kategori komparatif retrospektif. Berdasarkan uji analisa data dengan menggunakan repeated anova didapatkan ada perbedaan MAP pada pasien krisis hiperglikemia yang mendapatkan terapi rehidrasi cairan mulai jumlah terendah sampai jumlah tertingi selama terapi diberikan. Perubahan nilai MAP dalam penelitian ini untuk semua jumlah terapi dalam batas normal dimulai dari MAP sebelum terapi yang mendekati nilai kurang atau minimum sampai dengan MAP pada akhir terapi pada batas maksimal dari nilai normal MAP.  Hal ini menandakan pemberian terapi pada penelitian ini akan meningkatkan jumlah volume cairan tubuh dan peningkatan MAP  tanpa menyebakan tanda edema cerebral.Kata Kunci : Terapi rehidrasi, MAP (Mean Arterial Pressure), hiperglikemia krisis

Mefenamic acid is anti-inflammation non-steroid, which can hamper prostaglandin synthesis in the body tissue by hampering the siklooxigen enzyme. The purpose of this research is to find out the influence of Mefenamic acid toward the follicles development and progesterone level. This research is an experimental laboratory method. The subject of the research divided into five groups randomly selected and have been homogenized — one group as a control group and others as an experimental group with various dosages of Mefenamic acid treatment. The data is analyzed using a one-way Anova test. The results of this research are confirmed the significant difference of Grafian follicles, yellowish corpus luteum and progesterone level as the influence of Mefenamic acid. While there was no significant difference in tertiary follicles development. The decrease of corpus luteum is caused by Mephenamic acid activity to hamper the prostaglandin synthesis in the body tissue by hampering the siklooxigen enzyme. The prostaglandin can make follicles swelling and cause follicles fracture and make ovulation. The granulosis cell will make corpus luteum, which secreted progesterone hormone. Mefenamic acid was proven to avoid ovulation that blocked the formation of yellowish corpus luteum resulting in decreased blood progesterone level.

Brides-to-be are the right targets in an effort to improve the health of the period before pregnancy. Brides-to-be need to prepare reproductive health both in the bride and in the bride-to-be, so that after marriage can have a good health status in order to produce a quality generation. This service aims to increase knowledge, awareness, willingness and ability of the bride and groom to prevent the risk of pregnancy. The method used is to provide counseling to 10 respondents while  keeping their distance. Counseling is delivered with the theme of preventing the risk of pregnancy in brides-to-be with health education through booklet media. The results of the counseling showed a significant increase in public understanding of the problem from 48.15% to 87.35%. Based on these results, it is hoped that the public can apply this knowledge correctly in order to realize the highest degree of public health

Husband's support is a very important factor in the delivery process, because the husband can foster feelings of confidence and form a strong mentality towards his wife so that anxiety and fear disappear. In addition, cooperation between family and husband in providing good support for pregnant women can also eliminate the worry of pregnant women about the delivery process that will be carried out by pregnant women. The design of this research is correlational analytic. The population in this study were pregnant women in Tamanan Village, Kediri City in May 2022.  In this study, the sampling technique used simple random sampling The research instrument is a questionnaire sheet.The results showed that half (50%) of the respondents who received good husband support experienced mild anxiety, namely as many as 6 respondents, almost all (76.92%) who received sufficient husband support experienced moderate anxiety, namely as many as 20 respondents. Based on the results of statistical tests using the Spearman Rank correlation test (Rho) on the husband's support variable (X) and anxiety level (Y) obtained ρ value = 0.002 with a confidence level of α = 0.05, it can be concluded that ρ < α then H0 is rejected and H1 is accepted, meaning that there is a relationship between husband's support and anxiety levels in third trimester pregnant women. Based on the results of the study, there was an effect of husband's support on the anxiety of pregnant women in the third trimester in facing childbirth during the covid 19 pandemic in Tamanan Village, Kediri City in 2022. Suggestions for research sites to motivate husbands to increase their role psychologically throughout the process experienced by their wives includes pregnancy, childbirth, postpartum to the decision-making process in family planning.

Rhodamine b is misused as a food coloring. Excessive use is certainly harmful to health. The purpose of this study proves that Rhodamine b can reduce the number of primary follicles in the ovaries of white rats. The design of this study is true experimental with Post Test only control group design. Sample in the research used were female white rats (Rattus norvegicus) aged 2-3 months with a bodyweight of 150-250 grams in the amount of 10 animals which were divided into 2 groups: negative control group, positive control group. Rhodamine b is given for 36 days at a dose of 18 mg / 200 gr orally. The number of primary follicles is calculated by HE staining. Data were analyzed and conducted One Way Anova test. The results showed that the administration of Rhodamine b significantly reduced the number of primary follicles in the ovaries of white rats. This is because rhodamine b is capable of binding with halogen compounds which are reactive so that it can damage cells. Based on the results of the analysis showed that Rhodamine b can reduce the number of primary follicles in the ovaries of the white rat.