Although cord hemoglobin and mean corpuscular volume were not affected by maternal anemia, increased cord serum erythropoietin levels related to low maternal hemoglobin levels suggest an induced fetal erythropoiesis in maternal anemia.

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The purpose of this study is to introduce a two-stage solution approach for a large-scale home healthcare routeing and scheduling problem (HHCRSP). In the first part of the two-stage solution approach, a cluster-assign algorithm is employed, based on the home location and the time to obtain feasible clusters. In the second stage, using these clusters, route construction heuristics start to create schedules and routes, taking the side constraints of the model into consideration. Using the novelty of this two-stage solution approach, higher diversification is achieved with a series of newly-developed cross movement strategies. The computational results show that our solution approach offers certain advantages, such as an increase in the efficient use of human resources, and a decrease in the working time of nurses. OPSOMMINGDie doel van hierdie studie is om ʼn tweeledige oplossingsbenadering vir grootskaalse tuissorg roetebeplanning en skedulering voor te stel vir gesondheidsorg. In die eerste deel van die benadering word ʼn groepering-algoritme, gebaseer op die ligging van die tuiste en die tyd om vatbare groepe te vorm, toegepas. Tydens die tweede stap van die benadering word die groepe gebruik saam met roetebeplanning-heuristiek om skedules en roetes te skep terwyl die randvoor-waardes van die model in ag geneem word. Die tweeledige benadering bewerkstellig hoër diversifikasie met ʼn reeks nuut ontwikkelde kruisbeweging strategieë. Die gesimuleerde resultate toon dat die voorgestelde oplossingsbenadering sekere voordele inhou, onder andere die ʼn verhoging in die effektiewe aanwending van menslikehulpbronne en ʼn afname in die werktyd van verpleegsters.

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