Objectives. To analyse 1.5-year data of our newly established eye bank and to evaluate the factors affecting donor quality. Methods. Our bank's donor cornea data between July 2013 and November 2014 were retrospectively analysed. The effects of donor age, sex, and time from death to harvesting on the findings of specular microscopy were assessed. Results. A total of 139 corneas retrieved from 70 donors. The mean age of donors was 34.2±14.6 (5-64) years. The mean time from death to harvesting was 6.7±2.9 (1-13) hours; the mean time from collection to transplantation was 5.2±2.8 (1-14) days. Age had a significant negative correlation with mean endothelial cell count (ECC), a significant positive correlation between mean cell area (MCA) and standard deviation (SD). Time from death to harvesting had a significant negative correlation with cell count and 6A; it had a significant positive correlation with SD, the coefficient of variation, and MCA. Conclusion. According to the results of the present study, ECC, MCA, and SD levels were greater in younger donors. Endothelial morphology was altered as the time from death to harvesting was prolonged; however, the alteration in cell morphology was not severe enough to alter transplantation success with the corneas being harvested within the first 13 hours.Eur Res J 2016;2(1):30-35
Purpose The aim of this study was to detect early retinal vascular changes with optical coherence tomography angiography (OCTA) in type 1 diabetes mellitus (T1DM) patients without diabetic retinopathy and to evaluate the correlation of the results with carotid intima-media thickness (IMT). Design This is a case–control and cross-sectional study. Methods This study included 38 adult patients with T1DM, and 38 age and gender-matched healthy controls. Retinal and optic disc (OD) measurements were taken using OCTA. The carotid artery IMT of each patient was measured using Doppler ultrasonography. Superficial capillary plexus (SCP) and deep capillary plexus (DCP) vessel density, foveal avascular zone (FAZ), non-flow area (NFA) and foveal density (FD) were analysed in the fovea centred 6 × 6 mm macular area. The superficial capillary plexus and DCP were also scanned centred on the peripapillary region. The correlations between OCTA measurements and carotid IMT, duration of DM and haemoglobin A1c levels in patients with T1DM were evaluated. Results The mean values for carotid IMT were significantly higher in diabetic patients than in controls ( p < 0.001). The mean values for vessel density SCP, DCP and OD were significantly lower in the diabetic group ( p < 0.05). There were correlations between the carotid IMT and duration of T1DM and the evaluated parameters of OCTA. Conclusion Microvascular changes in the SCP and DCP in patients with T1DM without DR offer important data. OCTA can be used to detect early microvascular changes in patients with T1DM without DR. In addition, a relationship was found between SCP vascular dropout and carotid IMT.
ÖzetAmaç: Tatvan-Bitlis yöresinde görülen subkonjonktival hemorajili olgular›n s›kl›¤›n› ve iliflkili oldu¤u durumlar› saptamak. Gereç ve Yöntem: Kas›m 2008 ile Aral›k 2009 tarihleri aras›nda Tatvan Devlet Hastanesi GözHastal›klar› poliklini¤inde muayene edilen travmatik ve spontan subkonjonktival hemorajili 30 hastan›n tan›mlay›c› ve kesitsel bir çal›flmas›. Sonuçlar: Muayene edilen 6000 hastan›n aras›nda subkonjonktival hemorajili (30 göz) 30 (%0,5) hasta vard›. Hastalar›n 18'i bayan (%60), 12'si erkekti (%40). Ortalama yafllar› 31,2±16,0 (2-75 y›l) idi. Otuz hastan›n 14'ünde (%46,6) travmatik,16's›nda (%53,4) spontan subkonjonktival hemoraji vard›. Travmatik ve spontan subkonjonktival hemorajili hastalar›n ortalama yafllar› s›rayla 26,4±12,4 ve 35,5 ±17,9 idi (p=0,04). Subkonjonktival hemorajinin geliflmesi ile hastaneye ilk baflvuru aras›nda geçen süre spontan subkonjonktival hemorajili olgularda daha k›sayd› (≤3 gün, p=0,005). Spontan ve travmatik subkonjonktival hemorajili olgular aras›nda cinsiyet (p=0,7) ve tutulan göz (p=0,6) aç›lar›ndan istatistiksel olarak anlaml› bir farkl›l›k yoktu. Tutulum tüm hastalarda tek tarafl›yd›. Spontan subkonjonktival hemorajili hastalar›n %31,2' sinde iliflkili belirgin bir durum saptanmad›. Hipertansiyon (%31,2) en s›k iliflkili durumdu. Di¤er iliflkili durumlar ise kusma (%18,7), öksürme (%12,5) ve do¤umdu (%6,25). Travmatik subkonjonktival hemorajide yaralanmalar›n %71,4'ü evde oluflmufltu. Tart›flma: Tatvan-Bitlis yöresinde klini¤imize baflvuran hastalar›n %0,5'inde subkonjonktival hemoraji izlendi. Genç subkonjonktival hemorajili olgularda en önemli risk faktörünün travma, yafll›larda ise hipertansiyon oldu¤u görüldü. ( Result: There were 30 (0.5%) patients with subconjunctival haemorrhage (30 eyes) among 6000 examined patients. Eighteen (60%) patients were women and 12 (40%) were men, with a mean age of 31.2±16.0 (2-75) years. Among the 30 patients, 14 (46.6%) had traumatic and 16 (53.4%) had spontaneous subconjunctival haemorrhage. The mean age was 35.5±12.4 and 26.4±17.9 years for patients with spontaneous and traumatic subconjunctival haemorrhage, respectively (p=0.04). The period of time between the beginning of subconjunctival haemorrhage and initial admittance to the hospital was shorter in cases with spontaneous subconjunctival haemorrhage (≤3 days, p=0.005). There were no statistically significant differences between the patients with spontaneous and traumatic subconjunctival haemorrhage with respect to gender (p=0.7) and eye involvement (p=0.6). The condition was unilateral in all patients. In spontaneous subconjunctival haemorrhage, no apparent associated condition was found in 31.2%. Hypertension (31.2%) was the most frequent associated condition; others included vomiting (18.7%), coughing (12.5%) and delivery (6.2%). In traumatic subconjunctival haemorrhage, 71.4% of injuries occurred at home. Discussion: In the Tatvan-Bitlis region, subconjunctival haemorrhage was seen in 0.5% of patients that presented to the hospital. The major risk factor for subconj...
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