Analysis of the cornea donor data: an eye bank study

Abstract

Objectives. To analyse 1.5-year data of our newly established eye bank and to evaluate the factors affecting donor quality. Methods. Our bank's donor cornea data between July 2013 and November 2014 were retrospectively analysed. The effects of donor age, sex, and time from death to harvesting on the findings of specular microscopy were assessed. Results. A total of 139 corneas retrieved from 70 donors. The mean age of donors was 34.2±14.6 (5-64) years. The mean time from death to harvesting was 6.7±2.9 (1-13) hours; the mean time from collection to transplantation was 5.2±2.8 (1-14) days. Age had a significant negative correlation with mean endothelial cell count (ECC), a significant positive correlation between mean cell area (MCA) and standard deviation (SD). Time from death to harvesting had a significant negative correlation with cell count and 6A; it had a significant positive correlation with SD, the coefficient of variation, and MCA. Conclusion. According to the results of the present study, ECC, MCA, and SD levels were greater in younger donors. Endothelial morphology was altered as the time from death to harvesting was prolonged; however, the alteration in cell morphology was not severe enough to alter transplantation success with the corneas being harvested within the first 13 hours.Eur Res J 2016;2(1):30-35

Profile of donors and corneal tissue obtained through hospital cornea retrieval programme in a recently established eye bank of a tertiary care teaching hospital of eastern India

“…However, few comparable studies detailed early findings within first 2 years of establishment of EBs. [ 10 11 12 13 14 15 ] The largest EB of India started with only 20 corneal transplants in the year 1989. [ 11 ] In the present EB, 54 corneas were retrieved during the first 2 years of inception.…”

“…Another EB in Eastern India collected 130 corneas in the first 2 years. [ 12 ] An EB in Turkey reported early data over 17 months stating a retrieval of 139 corneas from 70 donors,[ 13 ] while the Central Eye Bank of Iran managed to collect 856 corneas in its initial 2 years but did not state reasons for high procurement rate. [ 16 ] A study from New Zealand reported a collection of 206, while the Lions Eye bank of South Australia reported a collection of 198 in the first 2 years.…”

“…The present study shows that tissue collection was more in the first year of establishment than the second year while in all other studies the numbers increase with time. [ 10 11 12 13 14 15 ] This is due to suspension of eye banking activities with the advent of the SARS-nCOV-2 (COVID-19) pandemic after March 2020,[ 9 17 ] with resumption of limited collection activities after August 2020. [ 18 ]…”

“…[ 5 ] The mean death-to-preservation interval in this study was 3.5 h with a median of 3 h. This was comparable to other studies from India which reported these to be 3.9 h and 2.8 h, respectively. [ 12 24 ] A study from Brazil had a mean DPI of 9.1 ± 4.7 h, while another from Turkey had 6.7 ± 2.9 h.[ 13 31 ] The norms for preservation vary according to the geography, warmer climates requiring lesser DPI for optimum outcomes. In temperate climates, a longer DPI may be acceptable.…”

The Evaluation of Ophthalmic Findings in Women Patients With Iron and Vitamin B12 Deficiency Anemia

“…The percentage of hexagonal cells as well decreases from 75% to about 60%. 22 All the participants in the present study were younger than 50 years in age; hence, the effect of age on endothelial parameters has been minimized.…”