Abstract:The aim of this study was to observe the cytotoxicity and apoptotic effects of nickel oxide nanoparticles on human cervix epithelioid carcinoma cell line (HeLa). Nickel oxide precursors were synthesized by an nickel sulphate-excess urea reaction in boiling aqueous solution. The synthesized NiO nanoparticles (<200 nm) were investigated by X-ray diffraction analysis and transmission electron microscopy techniques. For cytotoxicity experiments, HeLa cells were incubated in 50-500 μg/mL NiO for 2, 6, 12 and 16 hours. The viable cells were counted with a haemacytometer using light microscopy. The cytotoxicity was observed low in 50-200 μg/mL concentration for 16 h, but high in 400-500 μg/mL concentration for 2-6 h. HeLa cells' cytoplasm membrane was lysed and detached from the well surface in 400 μg/mL concentration NiO nanoparticles. Double staining and M30 immunostaining were performed to quantify the number of apoptotic cells in culture on the basis of apoptotic cell nuclei scores. The apoptotic effect was observed 20% for 16 h incubation.

The aim of the study is to investigate the leisure involvement and happiness levels of the individuals who have any fitness center membership. Screening model was used in the research. The sample group of the research was composed of a total of 599 voluntary participants, 260 being &ldquo;females&rdquo; and 339 being &ldquo;males&rdquo;, who were using fitness centers and were selected using improbable purposeful sampling method. &ldquo;Oxford Happiness Scale Short Form&mdash;OHS-F&rdquo;, developed by Hills and Argyle (2002) and adapted into Turkish by Doğan and Cotok (2011) along with &ldquo;Leisure Involvement Scale&mdash;LIS-F&rdquo;, developed by Kyle et al. (2007) and adapted into Turkish by Gurbuz et al. (2018) were used in the study in addition to &ldquo;Personal Information Form&rdquo;. Descriptive statistical method (frequency, arithmetic mean, standard deviation) was used for the identification of the distribution of the participants&rsquo; information. In order to determine if the data had normal distribution or not, Shapiro-Wilk test for normality was conducted and in consequence of this test, t-test, single factorial MANOVA, ANOVA and Pearson Correlation tests were administered upon determining that the data were in accordance with parametric test conditions. According to the findings, while there was no significant difference found in the happiness levels in line with the gender, marital status and education levels of the participants; a significant difference was determined in the leisure involvement levels according to education level and gender, and yet no significant difference was found between the leisure involvement level and marital status. Besides, a positively significant relationship was determined between the level of happiness and leisure involvement. The restraints as well as the evaluations for future studies were discussed in this sense.

The aim of the study is to investigate the relationship between the factors that prevent university students from attending to the recreational activities and the life satisfaction of the participants with the demographic variance. In accordance with this purpose, totally 263 students that are 140 (53.2%) “women” and 123 (46.8%) “men” who have been chosen with random sampling method attended to the study voluntarily.In this investigation, “Free Time Obstacles” ,which has been developed by Gürbüz and Karaküçük to determine the factors that might obstruct the attendance of the participants to the recreational activities and evaluates the factors that might prevent the university students from attending to recreational activities, was used. LSS (Life Satisfaction Scale) ,which has been created by Diener and his colleagues (1985) and adapted to Turkish by Yetim(1993), was used to evaluate the life satisfaction of the participants.Percentage (%) and frequency (f) methods were used to determine the distributions personal information of the participants; Shapiro Wilks normality test was used to determine whether data have normal distribution or not and as a result of these, after it is understood that the data are appropriate to the conditions of non-parametric test; Mann- Whitney U and Kruskall Wallis tests were used to determine the significant differences; and Spearman Correlation Test was carried out to determine the relationship between Free Time Obstacles Scale and Life Satisfaction Scale.As a result; it is observed that there is no significant relationship between Free Time Obstacles Scale and Life Satisfaction Scale; there is no significant difference between Life Satisfaction and gender variance considering gender variance; according to the Free Time Obstacles, there is only significant difference at the time sub-dimension; according to the doing sport, there is only significant difference at the Lack of Interest among the Free Time Obstacles; according to the Life Satisfaction, there is significant difference because of the people that don’t participate to the sportive activities. While according to the wealth level, a significant difference was determined at Life Satisfaction level, it is was determined that there is no significant difference at Free Time Obstacles and wealth level. Also, it is determined that there is a significant difference between Life Satisfaction and having difficulty in taking advantage of free time; there is a significant difference between having difficulty in taking advantage of free time and Free Time Obstacles at facility-service and time sub-dimension.Extended English abstract is in the end of PDF (TURKISH) file. ÖzetÇalışmanın amacı üniversite öğrencilerin rekreatif etkinliklere katılımlarına engel teşkil eden faktörler ile katılımcıların yaşam doyumları arasındaki ilişkinin demografik değişkenler ile birlikte incelenmesidir. Bu amaç doğrultusunda tesadüfi örnekleme yöntemiyle seçilmiş olan 140 (%53.2) “Kadın” ve 123 (%46.8) “Erkek” toplam 263 üniversite öğrencisi çalışmaya gönüllü olarak katılmıştır.Araştırmada, katılımcıların rekreasyonel faaliyetlere katılımlarına engel teşkil edebilecek faktörlerin belirlenmesi için Gürbüz ve Karaküçük tarafından geliştirilen üniversite öğrencilerinin rekreasyonel etkinliklerine katılmalarına engel teşkil edebilecek unsurları değerlendiren “Boş Zaman Engelleri” kullanılmıştır. Katılımcıların yaşam doyumlarını ölçmek amacıyla ise Diener ve arkadaşları (1985) tarafından geliştirilen ve Yetim (1993) tarafından Türkçe’ye uyarlanan YDÖ (Yaşam Doyumu Ölçeği) kullanılmıştır.Katılımcıların kişisel bilgilerinin dağılımlarının belirlenmesi için yüzde (%) ve frekans (f) yöntemleri; verilerin normal bir dağılıma sahip olup olmadığının belirlenmesi için Shapiro Wilks normallik testi uygulanmış ve bunun neticesinde verilerin non parametrik test koşullarına uygun olduğunun anlaşılmasından sonra anlamlı farklılıkların belirlenmesi için Mann-Whitney U ve Kruskall Wallis testleri, Boş Zaman Engelleri Ölçeği ile Yaşam Doyumu Ölçeği arasındaki ilişkinin belirlenmesi için ise Spearman Korelasyon testi uygulanmıştır.Sonuç olarak; boş zaman engelleri ile yaşam doyumu arasında, cinsiyet değişkeni açısından bakıldığında yaşam doyumu ile cinsiyet değişkeni arasında anlamlı bir farklılık olmadığı tespit edilmiştir. Boş zaman engelleri açısından ise sadece zaman alt boyutunda anlamlı bir farklılık olduğu, spor yapma durumuna göre boş zaman engelleri arasında da sadece ilgi eksikliği boyutunda anlamlı bir farklılık olduğu saptanmış, yaşam doyumuna göre incelendiğinde ise sportif etkinliklere katılmayan kişilerden kaynaklı anlamlı bir farklılığın olduğu ortaya çıkmıştır. Refah düzeyi değişkenine göre incelendiğinde yaşam doyumu düzeyinde anlamlı bir farklılık saptanmasına karşın boş zaman engelleri açısından refah düzeyinde ise anlamlı bir farklılık olmadığı tespit edilmiştir. Ayrıca yaşam doyumu ile boş zamanları değerlendirme güçlüğü çekmek arasında anlamlı bir farklılık olduğu, boş zaman değerlendirme güçlüğü çekmek ile boş zaman engelleri arasında ise tesis-hizmet ve zaman alt boyutlarında anlamlı bir farklılık olduğu tespit edilmiştir.

The purpose of this research is to examine the leisure constraints and level of perceived freedom of university students according to different variables. 250 university students in total, 174 (69%) of whom are males and 78 (31%) of whom are females selected by random sampling have voluntarily attended the research study. A survey model has been used in the study. The sample of the study consists of students studying at Istanbul University's Faculty of Sports Sciences. In order to identify the leisure obstacles of the participants, the Obstacles of Leisure Scale, which was developed by Alexandris and Carroll (1997) and adopted into Turkish by Karaküçük and Gürbüz (2007); and in order to identify the level of perceived freedom of the participants, the Perceived Freedom in Leisure Scale, which was developed by Witt and Ellis (1985) and adopted into Turkish by Yerlisu Lapa and Ağyar (2011), were used along with a personal information form prepared by the researcher as a data collection tool in the research. Percent (%) and frequency methods have been utilized to identify the distribution of the personal information of the participants and the ShapiroWilks normality test has been applied to identify whether data had normal distribution. MannWhitney U and Kruskall Wallis tests have been applied to determine the significant differences after it was determined that the data were suitable to non-parametric test conditions. According to the gender variable, no significant difference (except Individual Psychology) has been identified in the sub-dimensions of the obstacles of the leisure scale and perceived freedom in leisure scale (p>0.05). While there is a significant difference in all sub-dimensions of the perceived freedom in leisure scale (p<0.05), no significant difference has been found in the sub-dimensions of the obstacles of the leisure time scale (p>0.05) according to age. In conclusion, it has been determined that while there are no differences between the leisure obstacles according to the gender of the participants, the level of perceived freedom increases as the age increases.

The objective was to explore the relationship between person-based variables and work-related variables of presenteeism in four different private sector workplaces. Employees (N=413) filled in a questionnaire related to demographic and socio-economic characteristics, social networks, work-related factors, lifestyle factors and state of health. Presenteeism was assessed using the Stanford Presenteeism Scale 6 (SPS-6). The majority of respondents were male (77.2%), and mean age was 34.7±8.1 years. The prevalence of chronic conditions was 15.9%. The mean score for the SPS-6 was 19.9 (SD, 3.3). The female score was higher than the male score on the SPS-6 in this study. Total score was higher among workers who reported working at high speed. SPS-6 score was higher among individuals with a chronic health problem. Understanding of the workplace and personal factors related to presenteeism may support the health and well-being of workers.