The seminal observations of Dr. George Papanicolaou have grown, through the untiring efforts of many authors, into a universally accepted format of cytology reporting. This has helped immensely to improve the understanding of pathogenesis of cervical cancer. The insights into the complexity of interaction of the etiological and the host factors have further helped in reframing of the reporting system. The Bethesda System (TBS) stands out as a model of standardized reporting in cervicovaginal cytology. Apart from its reproducibility, it reflects the most current understanding of cervical cancer. The most important feature is its clinical relevance. Each category of this classification has clear clinical implications, which are based on solid evidence and worldwide consensus. Moreover, the authors have tried to keep it updated through continuous revisions, incorporating the technological and scientific advances. The component of specimen adequacy reflects the importance it has given to the quality assurance of the laboratory preparation. The minimization of categories, simple terminology, and the supporting image atlas – both in the print form and the web-based form, have made TBS an exemplary teaching-learning resource. The wide accessibility of TBS has been the most important factor in being adopted by a majority of pathology community all over the world.
Introduction Mesenteric fibromatosis-desmoid tumor of mesentery is a rare benign soft tissue tumor of mesentery. On CT, it mimics gastrointestinal stromal tumor (GIST). Case Report A 44-year-old female with small intestinal mass, preoperatively diagnosed radiologically and pathologically as GIST. Conclusion Mesenteric fibromatosis is a rare tumor often mistaken for GIST. Histopathology and immunohistochemistry is the key as management of both the tumors differs.
Introduction:A focal mass or a nodule in the liver has become easily accessible to the needle of a pathologist, courtesy the rising numbers of guided FNAC. Precise localisation of lesions helps in studying the cytological features in greater detail, of the area in question. A targeted needle aspiration achieves high rates of sensitivity and specificity with regard to the varied spectrum of the pathologies encountered in liver especially when correlated with serological tests. Thus present study was carried out with aim to assess the role of guided FNAC in the diagnosis of nodular lesions of liver and to study their cytomorphology. Materials and Methods: It is an observational, prospective study of 130 adequate aspirates from liver nodules done at tertiary care hospital over two year period. All patients presenting with nodular liver mass detected on imaging techniques were selected for FNAC under USG or CT guidance. Another pass was taken from the surrounding liver to ascertain the presence of parenchymal changes like fatty change, cirrhosis and dysplasia. Results: Adequate aspirates from 130 cases were studied. Lesions were categorised into non neoplastic (11) and neoplastic which were further classified benign (1), primary malignancies (31HCC, 4 cholangiocarcinoma) metastasis ( 72) and undifferentiated malignancies (11) respectively on cytology. Conclusion: Guided FNAC of the liver is a rapid simple and precise method of identifying the pathology in liver nodules. It can be a useful modality to triage the patients and decide further line of management.
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