Approximately 20% of all non-Hodgkin lymphoma (NHL) and 60% of indolent NHL (iNHL) cases are follicular lymphoma (FL), 1,2 a disease considered treatable, but not curable, with currently available therapeutic options.

The remarkable feature of the nonprofit sector is its astonishing diversity. This feature gets short shrift in the traditional market or governmental failure theories of the nonprofit sector. Drawing on Niklas Luhmann's concept of functional differentiation, we demonstrate that these theories are implicitly economy-and politics-biased. In seeking to overcome these biases, we show that nonprofits and nongovernmental organizations (NGOs) are better understood as those varieties of organizations whose primary focus is on function systems other than the economy and politics. We summarize this argument in the concept of organizational multifunctionality, which turns out to be likewise applicable to the for-profit sector.

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We explore the cross-fertilization potential between stakeholder theory and Niklas Luhmann’s social systems theory. Social systems, such as corporations or nonprofits, are defined by complexity reduction and operational closure, which may render them insensitive to their environment and undermine their sustainability. This vision resonates with stakeholder theory’s arguments on the importance of the corporate responsiveness to stakeholder interests. The suggested common ground between the theories yields novel insights into key concepts of stakeholder theory such as the contrast between the jointness of stakeholder interests and trade-off thinking, the normativity of the stakeholder idea, and the meaning of corporate social responsibility.

The Aufsess River catchment (97 km2) in northern Bavaria, Germany, is studied to establish a Holocene sediment budget and to investigate the sediment dynamics since the early times of farming in the third millennium BCE. The temporal characterization of the sediment dynamics is based on an intensive dating program with 73 OSL and 14 14C ages. To estimate soil erosion and deposition, colluvial and alluvial archives are investigated in the field by piling and trenching, supported by laboratory analyses. The sediment budget shows that 58% of these sediments are stored as colluvium in on- and foot-slope positions, 9% are stored as alluvium in the floodplains and 33% are exported from the Aufsess River catchment. Colluviation starts in the end-Neolithic ( c. 3100 BCE), while first indicators of soil erosion-derived alluviation is recorded c. 2–3 ka later. The pattern of sedimentation rates also displays differences between the colluvial and alluvial system, with a distinct increase in the Middle Ages ( c. 1000 CE) for the alluvial system, while the colluvial system records low sedimentation rates for this period. A contrast is also observed since Modern times ( c. 1500 CE), with increasing sedimentation rates for the colluvial system, whereas the alluvial system records decreasing rates. The different behavior of the colluvial and alluvial systems clearly shows the non-linear behavior of the catchment’s fluvial system. The results further suggest that human impact is most probably the dominant factor influencing the sediment dynamics of the catchment since the introduction of farming.