Purge air is injected through seals in the hub and shroud of axial turbines in order to prevent hot gas ingestion into the inter-stage gaps. An investigation into the losses involved with the injection of purge air has been undertaken, with the objectives of answering where the losses are generated, how they are generated, and what are the most effective ways for reducing them. In order to address these questions, a consistent framework for interpreting entropy generation as a measure of loss is developed for turbomachinery applications with secondary air streams. A procedure for factoring out distinct effects is also presented. These tools, applied to steady computations, elucidate four routes though which change in loss generation is brought about by injection of purge air: a shear layer between purge and main streams, interaction with the passage vortex system that generates radial velocity gradients, changes in wetted loss and tip clearance flow due to an increased degree of reaction, and the potential for reducing tip clearance flow for the case of purge flow injected from the shroud. An emphasis is placed on tracing these effects to specific purge flow characteristics that drive them. The understanding gained provides a rationale for the observed sensitivity of purge flow losses to the design parameters purge air mass fraction and swirl, compared to purge slot axial inclination and gap width. Pre-swirling of purge flow is less effective in mitigating losses in the case of shroud-injection, since there is a tradeoff with the tip clearance flow suppression effect.
Compressor efficiency variation with rotor tip gap is assessed using numerical simulations on an embedded stage representative of that in a large industrial gas turbine with Reynolds number ∼ 2 to 7×106. The results reveal three distinct behaviors of efficiency variation with tip gap. For relatively small tip gap (less than 0.8% span), the change in efficiency with tip gap is non-monotonic with an optimum tip gap for maximum efficiency. The optimum tip gap is set by two competing flow processes: decreasing tip leakage mixing loss and increasing viscous shear loss at the casing with decreasing tip gap. An optimum tip gap scaling is established and shown to satisfactorily quantify the optimal gap value. For medium tip gap (0.8%–3.4% span), the efficiency decreases approximately on a linear basis with increasing tip clearance. However, for tip gap beyond a threshold value (3.4% span for this rotor), the efficiency becomes less sensitive to tip gap as the blade tip becomes more aft-loaded thus reducing tip flow mixing loss in the rotor passage. The threshold value is set by the competing effects between increasing tip leakage flow and decreasing tip flow induced mixing loss with increasing tip gap. Thus, to desensitize compressor performance variation with blade gap, rotor should be tip aft-loaded and hub fore-loaded while stator should be tip fore-loaded and hub aft-loaded as much as feasible. This reduces the opportunity for clearance flow mixing loss and maximizes the benefits of reversible work from unsteady effects in attenuating the clearance flow through the downstream blade-row. The net effect can be an overall compressor performance enhancement in terms of efficiency, pressure rise capability, robustness to end gap variation and potentially useful operable range broadening.
Background Dengue (DENV), chikungunya (CHIKV) and Zika virus (ZIKV), are mosquito-borne viruses of medical importance in most tropical and subtropical regions. Vector control, primarily through insecticides, remains the primary method to prevent their transmission. Here, we evaluated insecticide resistance profiles and identified important underlying resistance mechanisms in populations of Aedes aegypti and Ae. albopictus from six different regions in Cameroon to pesticides commonly used during military and civilian public health vector control operations. Methods Aedes mosquitoes were sampled as larvae or pupae between August 2020 and July 2021 in six locations across Cameroon and reared until the next generation, G1. Ae. aegypti and Ae. albopictus adults from G1 were tested following World Health Organization (WHO) recommendations and Ae. aegypti G0 adults screened with real time melting curve qPCR analyses to genotype the F1534C, V1016I and V410L Aedes kdr mutations. Piperonyl butoxide (PBO) assays and real time qPCR were carried out from some cytochrome p450 genes known to be involved in metabolic resistance. Statistical analyses were performed using Chi-square test and generalized linear models. Results Loss of susceptibility was observed to all insecticides tested. Mortality rates from tests with 0.25% permethrin varied from 24.27 to 85.89% in Ae. aegypti and from 17.35% to 68.08% in Ae. albopictus. Mortality rates for 0.03% deltamethrin were between 23.30% and 88.20% in Ae. aegypti and between 69.47 and 84.11% in Ae. albopictus. We found a moderate level of resistance against bendiocarb, with mortality rates ranging from 69.31% to 90.26% in Ae. aegypti and from 86.75 to 98.95% in Ae. albopictus. With PBO pre-exposure, we found partial or fully restored susceptibility to pyrethroids and bendiocarb. The genes Cyp9M6F88/87 and Cyp9J10 were overexpressed in Ae. aegypti populations from Douala sites resistant to permethrin and deltamethrin. Cyp6P12 was highly expressed in alphacypermethrin and permethrin resistant Ae. albopictus samples. F1534C and V1016I mutations were detected in A. aegypti mosquitoes and for the first time V410L was reported in Cameroon. Conclusions This study revealed that Ae. aegypti and Ae. albopictus are resistant to multiple insecticide classes with multiple resistance mechanisms implicated. These findings could guide insecticide use to control arbovirus vectors in Cameroon.
Compressor efficiency variation with rotor tip gap is assessed using numerical simulations on an embedded stage representative of that in a large industrial gas turbine with Reynolds number ∼ 2 × 106 to 7 × 106. The results reveal three distinct behaviors of efficiency variation with tip gap. For relatively small tip gap (less than 0.8% span), the change in efficiency with tip gap is nonmonotonic with an optimum tip gap for maximum efficiency. The optimum tip gap is set by two competing flow processes: decreasing tip leakage mixing loss and increasing viscous shear loss at the casing with decreasing tip gap. An optimum tip gap scaling is established and shown to satisfactorily quantify the optimal gap value. For medium tip gap (0.8%–3.4% span), the efficiency decreases approximately on a linear basis with increasing tip clearance. However, for tip gap beyond a threshold value (3.4% span for this rotor), the efficiency becomes less sensitive to tip gap as the blade tip becomes more aft-loaded thus reducing tip flow mixing loss in the rotor passage. The threshold value is set by the competing effects between increasing tip leakage flow and decreasing tip flow induced mixing loss with increasing tip gap. Thus, to desensitize compressor performance variation with blade gap, rotor should be tip aft-loaded and hub fore-loaded while stator should be tip fore-loaded and hub aft-loaded as much as feasible. This reduces the opportunity for clearance flow mixing loss and maximizes the benefits of reversible work from unsteady effects in attenuating the clearance flow through the downstream blade-row. The net effect can be an overall compressor performance enhancement in terms of efficiency, pressure rise capability, robustness to end gap variation, and potentially useful operable range broadening.
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