Understanding the causes of interstate conflict continues to be a primary goal of the field of international relations. To that end, scholars continue to rely on large datasets of conflict in the international system. This paper introduces the latest iteration in the most widely used dataset on interstate conflicts, the Militarized Interstate Dispute (MID) 4 data. In this paper we first outline the updated data-collection process for the MID4 data. Second, we present some minor changes and clarifications to the coding rules for the MID4 datasets, as well as pointing out how the MID coding procedures affect several notable “close call” cases. Third, we introduce updates to the existing MID datasets for the years 2002–2010 and provide descriptive statistics that allow comparisons of the newer MID data to prior versions. We also offer some best practices and point out several ways in which the new MID data can contribute to research in international conflict.

Background:Patients with malignant pleural effusions (MPEs) generally have advanced disease with poor survival and few therapeutic options. Cells within MPEs may be used to stratify patients for targeted therapy. Targeted therapy with poly(ADP ribose) polymerase inhibitors (PARPi) depends on identifying homologous recombination DNA repair (HRR)-defective cancer cells. We aimed to determine the feasibility of assaying HRR status in MPE cells.Methods:A total of 15 MPE samples were collected from consenting patients with non-small-cell lung cancer (NSCLC), mesothelioma and ovarian and breast cancer. Primary cultures were confirmed as epithelial by pancytokeratin, and HRR status was determined by the detection of γH2AX and RAD51 foci following a 24-h exposure to rucaparib, by immunofluorescence microscopy. Massively parallel next-generation sequencing of DNA repair genes was performed on cultured MPE cells.Results:From 15 MPE samples, 13 cultures were successfully established, with HRR function successfully determined in 12 cultures. Four samples – three NSCLC and one mesothelioma – were HRR defective and eight samples – one NSCLC, one mesothelioma, one sarcomatoid, one breast and four ovarian cancers – were HRR functional. No mutations in DNA repair genes were associated with HRR status, but there was probable loss of heterozygosity of FANCG, RPA1 and PARP1.Conclusions:HRR function can be successfully detected in MPE cells demonstrating the potential to stratify patients for targeted therapy with PARPi.

The UK, like other countries, has seen a proliferation of declarations of local climate emergencies. While these declarations have been interpreted as a demonstration of ambition, little is known about how and why they actually came about when they did and the implications this will have for what happens next. Focusing on London, UK, we present evidence collected via semi-structured interviews with experts and practitioners involved in the propagation of climate emergency declarations to critically explore how and why these declarations emerged, and the various different roles they are perceived to play for different local actors. Our findings reveal four journeys to local government declaration of a climate emergency (made actively from above, passively from above, actively from below, and passively from across) and three interwoven purposes (statements of intent, acting as a political gesture, and stimulating local action). We argue that these three purposes combine and coalesce to correlate the declaration of climate emergency with a local responsibility for emissions reduction, leaving little analytical space to question the scalar disconnect between the immediacy of the narrative at local scales and the slow-burning (and) global nature of the threat in question. If these emergency declarations are to be an opportunity for change in the governance of climate change, then the question of ‘what next?’ requires more in-depth, thorough and constructive engagement with the type of climate action the declarations are expected to induce while considering how this aligns with existing responsibilities and resource bases of local government.

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Much of the data used to measure conflict is extracted from news reports. This is typically accomplished using either expert coders to quantify the relevant information or machine coders to automatically extract data from documents. Although expert coding is costly, it produces quality data. Machine coding is fast and inexpensive, but the data are noisy. To diminish the severity of this tradeoff, we introduce a method for analyzing news documents that uses crowdsourcing, supplemented with computational approaches. The new method is tested on documents about Militarized Interstate Disputes, and its accuracy ranges between about 68 and 76 percent. This is shown to be a considerable improvement over automated coding, and to cost less and be much faster than expert coding.

This article examines student paramedics' perspectives of the Paramedic Educator (PEd) role, focusing on specific mentoring qualities that impact upon their learning. Furthermore, it aims to identify ‘mentoring’ issues specific to the paramedic profession. The study used semi-structured interviews with university paramedic students. The key attributes of a ‘mentor’ as identified in the nursing and healthcare literature were found to be relevant to the paramedic profession. Participants identified current challenges in practice specific to the paramedic profession. Questions are raised regarding the extent to which the culture of mentorship within ambulance services is sufficiently established to support students and PEds; the status quo poses significant challenges for students wishing to join the profession.

Urban planning and design in the 21st century is increasingly focusing on sustainability, illustrated by the proliferation of greener cities. While operational definitions and the actual planning of these cities can vary considerably (e.g., eco cities and low carbon cities), conceptually, at least, these terms overlap, particularly with regard to how they attempt to achieve both greener infrastructural design and healthier human lifestyles. This paper presents the findings of survey-based research carried out within Lingang New Town in Shanghai in 2019. In the cities of the Global North, the interplay between green infrastructural provision and public health has been of interest, especially in the context of social inequalities; however, there is little research from rapidly urbanizing countries where green urbanism is being increasingly promoted. Using this newly constructed example, we identified a clear positive correlation between moving to a green city and the adoption of healthier lifestyles. The structural equation modelling results suggest that behaviors around the use of green space as well as perceptions of different green space have notable impacts on residents’ physical health, measured by body mass index (BMI). The findings further illustrate systemic inequalities among private housing, rental housing and public housing typologies with regard to the distribution of health benefits.

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