Objectives
Approaches to improve saphenous vein (SV) patency in coronary artery bypass graft (CABG) surgery remain relevant. This study aimed to evaluate the effects of different preservation solutions, and different pressures of intraluminal distention on the endothelium of SV segments in CABG.
Methods
42 SV segments obtained from twelve patients undergoing CABG were divided into seven groups. Group 1 (control) was prepared without preservation or intraluminal distension, while the other six groups were preserved in autologous heparinized autologous arterial blood (AAB), or normal saline (NS), with distention pressures of 30 mmHg, 100 mmHg and 300 mmHg. To assess the effects of using these solutions and pressures on the endothelium, the grafts were analyzed by scanning electron microscopy (SEM), with measurement of endothelial damage degree.
Results
Segments in group 1 showed minimal endothelial damage. SV grafts preserved with NS had significantly greater endothelial damage both compared to the control group and compared to groups preserved with AAB (p < 0.001). Segments distended with pressures up to 100 mmHg showed less damage when compared to those distended at 300 mmHg, with the ones subjected to higher pressures presenting a maximum degree of damage, with considerable loss and separation of endothelial cells, extensive foci of exposure of the basement membrane, and numerous fractures of the intimate layer, without differences regarding the solution used.
Conclusions
Preparation of SV using NS and with intraluminal distension pressures above 100 mmHg are factors related to increased damage to the venous endothelium.
Objetivos: Avaliar o conhecimento de estudantes de ensino médio acerca de suporte básico de vida (SBV). Método: Estudo realizado em escola pública, com estudantes de ensino médio. Foram seguidos os passos: 1) aplicação de um questionário, com o objetivo de averiguar os conhecimentos prévio dos alunos sobre o tema; 2) apresentação de uma conferência dialogada sobre a cadeia de sobrevivência em situações de parada cardiorrespiratória (PCR); 3) desenvolvimento de habilidades práticas com os estudantes de como atuar frente à uma situação de PCR, seguindo a cadeia de sobrevivência; 4) aplicação do mesmo questionário, com o objetivo de averiguar os conhecimentos dos alunos após o desenvolvimento da atividade. Resultados: A média de acertos quando se comparou o pré e pós-teste considerando perguntas referente à cadeia de sobrevivência, atendimento pré-hospitalar pelo SAMU, reanimação cardiopulmonar (RCP) e PCR apresentou diferença significativa (teste de wilcoxon p<0,001). Conclusão: Houve significativa aquisição de conhecimentos teóricos por estudantes de ensino médio acerca da cadeia de sobrevivência em SBV após intervenção teórico-prática. Dessa forma, inferindo que estas ações de extensão universitária contribuem para educar a população, podendo resultar em diminuição da mortalidade em casos de PCR em ambiente extra-hospitalar.
Mucoepidermoid carcinoma (MEC) is a common malignant tumor composed of mucinous cells, clear cells and squamoid tumor cells. It is usually localized on the salivary glands, however can very rarely be intraosseous. This tumor affects women more than men and is more common in the mandible. In this report, we present a case of a 45-year-old woman with a painless intraoral mass for 10 years which was repeatedly misdiagnosed, evolving into an extensive lesion. After an appropriate approach, she was diagnosed with MEC of the mandible and submitted to a left hemimandibulectomy accompanied by microsurgical reconstruction with excellent results.
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