The close similarity of the sensitivity and specificity of FFR and d-FFR, around almost identical cutoff values (0.75 versus 0.76), confirms the physiological validity of FFR as a clinical standard. In clinical practice, FFR remains the index of choice for assessment of the functional severity of moderate coronary artery stenoses.
We experimentally demonstrated the simultaneous nonlinearity mitigation of PDM-16QAM WDM signals using complementary-spectrally-inverted optical phase conjugation (CSI-OPC). We achieved reserved-band-less, guard-band-less, and polarization independent OPC based on periodically poled LiNbO3 waveguides. By employing the CSI-OPC, 2.325-THz-band (93 × 25 GHz) complementary spectral inversion was achieved while retaining the original WDM bandwidth. A Q2-factor improvement of over 0.4 dB and a 5120 km transmission with a Q2-factor above the FEC limit were confirmed using a 10-channel WDM transmission at the signal band center and signal band edge. We then demonstrated the mitigation of the nonlinear impairments in a 3840 km long-haul WDM signal transmission for all 92-channel 180-Gbit/s PDM-16QAM quasi-Nyquist-WDM signals.
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