Itai-itai disease was first noticed in the Junzu River basin region in Toyama prefecture in central Japan around the 1930s. However, it was not identified as a cadmium poisoning disease until the 1960s. A local physician, with cooperation from outside experts, confirmed that the disease was caused by pollution from the Kamioka mine (owned by the Mitsui Mining & Smelting Company Ltd) located in the upstream region of the river. In the mid-1960s, the victims of Itai-itai disease filed a suit against the company and won their case in 1972. The victims received compensation and signed a pollution control agreement with the company. The case of Itai-itai disease is a rare example of successful pollution control in Japan: the annual inspections of the ensuing 40 yr, based on the pollution control agreement, show a reduction of cadmium concentrations in the river to natural levels. By analyzing the roles of various experts involved, this case study has contributed substantially to an understanding of the nature of expertise and the significance of public participation in the resolution of environmental problems.
The favorable and relatively rapid reception of Mendeleev's periodic table of the elements can be attributed, in part at least, to his social connections. These connections were evident in the recently organized Russian Chemical Society. In addition, Mendeleev enjoyed the support of the editorial board of the journal of the German Chemical Society.
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