Itai-itai Disease: Lessons for the Way to Environmental Regeneration

Kaji, Masanori

doi:10.1007/978-3-319-15353-7_7

Cited by 5 publications

(3 citation statements)

References 5 publications

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“…More so, the spate of industrialization, urbanization and anthropogenic activities (such as mining, smelting, paint production, incineration, agriculture, fossil fuel combustion), and natural events (such as weathering, erosion, volcanic eruptions) has resulted in an increase in the severity of environmental heavy metal pollution and exposure (He, Yang and Stoffella, 2005;Patra et al, 2007;Nagajyoti, Lee and Sreekanth, 2010;Chen, Chen and Dong, 2012;Tchounwou et al, 2012). However, anthropogenic activities contribute the highest source of environmental contamination (Mensah et al, 2009;Tchounwou et al, 2012;Jaishankar et al, 2014) as illustrated by the role of mining activities in the Zamfara state (Nigeria) lead poisoning (Burki, 2012) and the Toyama Prefecture (Japan) Itai-Itai disease (cadmium poisoning) incidence (Kaji, 2015). With the impact of both heavy metals widely recognised globally as the most prevalent environmental contaminants with farreaching toxicity effects.…”

Section: Introductionmentioning

confidence: 99%

Tissue Lead and Cadmium Levels and Associated Haematological Changes in Goats Slaughtered at The Bodija Abattoir, Ibadan

Jubril

Sijuwola

Adekola

et al. 2020

Turkish JAF Sci.Tech.

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Heavy metal environmental contamination consequent of anthropogenic factors has become a global concern with cadmium and lead constituting a major public health, livestock and ecological threat. This study, therefore, uses goats (as sentinel animals) raised in 2 different regions based on their mining history (previous and existing) to evaluate exposure to cadmium and lead and their consequent toxicities and pathological changes. A total of 130 goats (composed of 88 goats which constitute the suspected exposure (SE) group and 44 goats, the suspected unexposed (SU) group) were sampled. Blood and tissue samples (liver, kidney and muscles) were analysed for lead and cadmium levels using Atomic Absorption Spectrophotometer along with the complete blood count analysis. The mean blood lead levels (BLLs) and cadmium levels (BCLs) in the goats from the SE groups were 14.59 and 3.12 µg/dl respectively, which were significantly higher than the SU groups (9.23 and 0.46 µg/dl respectively) A significantly higher frequency of goats in the SE (93.18%) also had an elevated BLLs compared to the SU group (78.57%). The levels of tissue lead and cadmium in both the SE and SU groups were found significant and higher than the FAO/WHO maximum limits. The packed cell volume, red blood cell count, and haemoglobin concentration were found significantly lower, and the platelet count and some leucocyte parameters (total white blood cell, neutrophil, eosinophil, and monocyte count) were found significantly higher in the SE group. The elevated cadmium and lead level in both groups further highlight the ubiquitous spread of cadmium and lead environmental contamination in both study regions and the direct risk of exposure to human and animals in Nigeria. The relative differences in the observed pathological changes in the two study groups also suggest the influence of the environmental heavy metal pollution and exposure levels on health.

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Section: Introductionmentioning

confidence: 99%

Tissue Lead and Cadmium Levels and Associated Haematological Changes in Goats Slaughtered at The Bodija Abattoir, Ibadan

Jubril

Sijuwola

Adekola

et al. 2020

Turkish JAF Sci.Tech.

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“…The metal accumulation in both urban and rural environments above the background concentrations may affect ecosystems including plants and animals and has been causing a serious threat to human health. Some of the serious examples of metal toxicity include Minamata disease (methylmercury poisoning) [4] and itai-itai disease (cadmium poisoning) [5].…”

Section: Introductionmentioning

confidence: 99%

Heavy Metals in Urban Dust

Nakajima¹,

Aryal²

2018

Heavy Metals

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Urban dust is contaminated by pollutants from various diffused sources and is often difficult to be controlled. It elevates the background heavy metal exposure level to humans and ecosystems in and around urban area and may give an apparent or hidden impact. In this chapter, the recent studies on heavy metals in the urban dust are summarized. First, the heavy metal pollution of the dust in the atmosphere and on the road surface is described. Then, the process of road runoff and subsequent infiltration to the soil is discussed from the viewpoint of heavy metal mobility. Finally, the ecotoxicity of road dust is shown, and the causal pollutants in the dust are discussed.

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“…At a policy level, a number of interventions have aimed to reduce cadmium exposure through both remediation and prevention [38]. In the best-known example, hundreds of victims -primarily women -developed Itai-itai disease from cadmium pollution emanating from the Mitsui Kamioka mine in Toyama Prefecture, Japan, over several decades until the 1960s [39]. The victims eventually succeeded with extensive advocacy and legal action, and decontamination measures were implemented which significantly remediated the pollution [40].…”

mentioning

confidence: 99%

Interventions to reduce cadmium exposure in low- and middle-income countries during pregnancy and childhood: A systematic review

Sripada

Lager

2022

J Glob Health

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Background Exposure to the toxic metal cadmium is widespread globally and especially prevalent in low- and middle-income countries (LMICs). Early life (from pregnancy through childhood) is a vulnerable window for exposure. Therefore, interventions in low- and middle-income countries to prevent or reduce early life exposure to cadmium may be relevant for improving public health. Methods We systematically reviewed five databases (Scopus, Web of Science, Global Health Medicus, Greenfile, and PubMed). A synthesis without meta-analysis (narrative synthesis) was used for data analysis due to the wide heterogeneity of included studies. Study quality and risk of bias were assessed using modified GRADE criteria. Results 4098 articles were returned by the search and a total of 26 studies from 21 LMICs were included in this review, ranging from policies to clinical treatment, rehabilitation and clean-up methods for agricultural soil, interventions for nutrition and cooking, and anti-pollution strategies at the household level. The interventions targeted children, pregnant and postpartum women, and/or women of childbearing age. While several studies provided some evidence of effectiveness, none appeared to offer a realistic solution for cadmium pollution at scale. Agricultural and food preparation studies were relatively frequent, particularly related to rice. Studies on air filtration during pregnancy indicated some effectiveness in reducing indoor cadmium exposures. Conclusions Cadmium pollution is a persistent and widespread threat to children’s health with few identified solutions. Long-lasting damage to children’s health starting in the earliest years should motivate investment in higher-quality interventions, innovations, and further research. Registration PROSPERO (CRD42021235435).

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Itai-itai Disease: Lessons for the Way to Environmental Regeneration

Cited by 5 publications

References 5 publications

Tissue Lead and Cadmium Levels and Associated Haematological Changes in Goats Slaughtered at The Bodija Abattoir, Ibadan

Tissue Lead and Cadmium Levels and Associated Haematological Changes in Goats Slaughtered at The Bodija Abattoir, Ibadan

Heavy Metals in Urban Dust

Interventions to reduce cadmium exposure in low- and middle-income countries during pregnancy and childhood: A systematic review

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