In the present study, we test the main hypothesis that infants' understanding of others' needs translates into helping behavior, when critical motor and social competencies have emerged, early in the second year. We assessed the understanding of others' needs in an eye-tracking paradigm and the helping behavior of 10-(n = 41) and 16-month-olds (n = 37). Furthermore, we assessed the motor and social abilities of 16-month-olds. Critically, while infants understood others' needs already at 10 months, fine motor and social interaction skills moderated the link between infants' prosocial understanding and helping behavior at 16 months. This provides first evidence that infants' helping behavior relates to their understanding of others' needs. Furthermore, we found that fine motor, gross motor, and social interaction skills predicted early helping behavior by themselves. These findings highlight that the emergence of infants' helping behavior is the result of a developmental system that includes infants' understanding of others' needs and also their motor and social competencies. The link between infants' understanding of others' needs and their early helpful actions provide further support for the prosocial nature of early helping behavior. K E Y W O R D Shelping behavior, motor development, social interaction, understanding others' needs

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Background Plexiform schwannoma is one of the least common variants of schwannoma, accounting for only 5% of all schwannoma cases. It generally occurs in the skin and subcutaneous tissues and is uncommon in deep soft tissue or viscera. We present an extremely rare case of plexiform schwannoma arising from the peripancreatic plexus. Case presentation A 29-year-old man presented with hyperglycemia detected during a medical checkup. He was diagnosed with type 1 diabetes based on the clinical findings and laboratory tests. During the diagnostic process for diabetes, a 2.5 cm mass was incidentally detected in the pancreas by abdominal ultrasound. Contrast-enhanced computed tomography revealed a mass that was gradually enhanced at the body and tail of the pancreas. Magnetic resonance imaging revealed low signal intensity of the mass on T1-weighted images and high signal intensity on T2-weighted and diffusion-weighted images. Magnetic resonance cholangiopancreatography showed no abnormal findings in the main pancreatic duct. Endoscopic ultrasonography (EUS) showed a lobulated, low-echoic mass with a clear boundary. EUS-guided fine needle biopsy was performed, and spindle-shaped cells that were diffusely immunopositive for S-100 and negative for c-kit and desmin were detected, resulting in a diagnosis of a neurogenic tumor arising from the pancreas or the peripancreatic nerve plexus. The patient underwent laparoscopic spleen-preserving distal pancreatectomy. Although the tumor was connected to the splenic plexus, the splenic artery could be divided along its adventitial plane. Macroscopic findings of the excised tumor consisted of multiple yellowish-white nodules, and its histopathological features were consistent with plexiform schwannoma. There was no pancreatic tissue on the dorsal surface of the tumor, which suggested that the tumor arose from the peripancreatic nerve plexus. Conclusions The findings documented herein can aid in the differential diagnosis of peripancreatic schwannoma and in planning appropriate treatment.

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