Introduction:Chronic renal failure exposes patients to the risk of several complications, which will affect every aspect of patient’s life, and eventually his hope. This study aims to determine the effect of stress management group training on hope in hemodialysis patients.Method:In this quasi-experimental single-blind study, 50 patients with renal failure undergoing hemodialysis at Motahari Hospital in Jahrom were randomly divided into stress management training and control groups. Sampling was purposive, and patients in stress management training group received 60-minute in-person training by the researcher (in groups of 5 to 8 patients) before dialysis, over 5 sessions, lasting 8 weeks, and a researcher-made training booklet was made available to them in the first session. Patients in the control group received routine training given to all patients in hemodialysis department. Patients’ hope was recorded before and after intervention. Data collection tools included demographic details form, checklist of problems of hemodialysis patients and Miller hope scale (MHS). Data were analyzed in SPSS-18, using Chi-square, one-way analysis of variance, and paired t-test.Results:Fifty patients were studied in two groups of 25 each. No significant difference was observed between the two groups in terms of age, gender, or hope before intervention. After 8 weeks of training, hope reduced from 95.92±12.63 to 91.16±11.06 (P=0.404) in the control group, and increased from 97.24±11.16 to 170.96±7.99 (P=0.001) in the stress management training group. Significant differences were observed between the two groups in hope scores after the intervention.Conclusion:Stress management training by nurses significantly increased hope in hemodialysis patients. This low cost intervention can be used to improve hope in hemodialysis patients.
Forestist is an international, scientific, open access periodical published in accordance with independent, unbiased, and double-blinded peer-review principles. The journal is the official publication of İstanbul University-Cerrahpaşa Faculty of Forestry and continues publication since 1951. Forestist is published biannually on January and July and the publication language of the journal is English. Forestist aims to contribute to the literature by publishing manuscripts at the highest scientific level on all fields of forestry. The journal publishes original articles, reviews, and brief notes that are prepared in accordance with the ethical guidelines. The scope of the journal includes but not limited to; forest, forestry, forestry based industries, landscape and environment. The target audience of the journal includes specialists and professionals working and interested in all disciplines of forestry.
Alzheimer's disease (AD) has been reported to be linked with diabetes mellitus and insulin resistance. Adiponectin (ADN), an adipocytokine secreted from adipose tissue, is involved in the regulation of insulin sensitivity, energy homeostasis, and mitochondrial dysfunction. In this study, we examined the effect of ADN on passive avoidance memory in animal model of sporadic AD (sAD). On days 1 and 3 after cannulation, rats received intracerebroventricular (icv) injection of streptozotocin (STZ) (3 mg/kg). Thirty minutes before the learning process, animals received saline or ADN in different doses (6, 60, and 600 µg). The step-through latency (STL) and total time spent in the dark compartment (TDC) were recorded and analyzed. In STZ-treated rats, STL was significantly decreased, whereas TDC showed a dramatic increase. In ADN-treated rats, STL was significantly increased (P < 0.01) in all treatment doses. The number of entries was decreased in all applied doses; however, TDC was reduced only by the application of 6 ng of ADN (P < 0.05). It can be concluded that ADN is useful to improve the STZ-induced memory impairment. This study showed, for the first time, that icv administration of ADN could improve the memory acquisition in animal model of sAD.
Objective:To evaluate the effects of Catechin (CAT) on memory acquisition and retrieval in the animal model of sporadic alzheimer’s disease (sAD) induced by intracerebroventricular (icv) injection of streptozotocin (STZ) in passive avoidance memory test.Methods:Thirty adult rats were divided into 5 experimental groups (n=6). Animals were treated by icv saline/STZ (3 mg/kg) injection at day one and 3 after cannulation. The STZ+CAT group received 40 mg/kg CAT by daily gavages for 10 days, after icv STZ treatment and before training. The step-through latency (STL) and time spent in the dark compartment (TDC) were evaluated to examine the memory acquisition and retrieval. All tests were performed in Qom University of Medical Sciences, Qom, Iran, from April to December 2013.Results:The STZ treatment significantly decreased STL and increased the number of entries to the dark compartment on the training day. It also increased TDC, on day one and 7 after training. Pre-training gavage of CAT reversed the STL significantly (p=0.027). The CAT treatment also decreased the TDC in both early and late retrieval, in respect to STZ group.Conclusion:This data suggests that CAT as an antioxidant could improve both memory acquisition and retrieval in the animal model of sAD.
Background: Nutrition and dietary habits is one of the determinant factor on glycemic control of diabetes mellitus. This study aims to investigate the association between type 1 diabetes mellitus (T1DM) and diet in the first two years of life as well as a select group of demographic variables. Methods: This case-control study was conducted on 76 children with T1DM and 209 non-diabetic children selected through convenience sampling from the population of people visiting the community health centers of the city of Jahrom, Iran. The required data were collected by a questionnaire of diet and demographic information completed by the mothers of the children. The data were analyzed using logistic regression and adjusted odds ratio. Results: Finally, the results of multiple backward logistic regression showed that the studied factors had a significant association with T1DM (P < 0.05), including body mass index (BMI) less than 18 kg/m2 for mothers before pregnancy (OR: 4.4, 95% CI: 1.61 to 11.97), mothers without a history of diabetes (OR: 0.02, 95% CI: 0.001 to 0.60), mother’s weight before pregnancy (OR: 0.88, 95% CI: 0.84 to 0.91), mother’s excess weight during pregnancy (OR: 0.83, 95% CI: 0.75 to 0.93), exclusive breastfeeding for more than six months (OR: 0.19, 95% CI: 0.03 to 0.96), low weight gain in the first two years of life (OR: 6.98, 95% CI: 2.16 to 22.5), and the breastfeeding less than 12 months (OR: 10.52, 95% CI: 1.62 to 66.64). Conclusion: BMI less than 18 kg/m2 for mothers before pregnancy, low weight gain in the first two years of life, and breastfeeding less than 12 months increased the risk of developing T1DM in children.
Background: The importance of healthy nutrition in increasing immunity and reducing disease has been identified for many years. Nutrient deficiencies lead to decreased immune function and thus increase the incidence or exacerbation of infections. This study aimed to investigate the knowledge, attitude, and nutritional function associated with COVID-19 disease in people of Yazd. Methods: This descriptive and analytical study was conducted in 2021. The sample size was 420 adults in Yazd referring to health centers. Research tools included demographic checklist and questionnaire of nutritional knowledge, attitude, and practices related to COVID-19. Results: The mean scores of nutritional knowledge, attitude, and practices related to COVID-19 in people of Yazd were 21.35 ± 4.54, 20.74± 3.58, and 38.99 ± 7.39, respectively. There was a statistically significant difference between knowledge and level of education and history of COVID-19 and practice with gender and history of COVID-19. The most important source of information for people was cyberspace. Conclusion: Knowledge of the nutritional factors affecting a disease can affect people's attitudes and practices. So that lack of sufficient knowledge and misunderstanding among people can increase the prevalence of the disease and delay the recovery of COVID-19. Due to the importance of this matter, the need to implement educational programs to inform people about proper practices should be considered.
Background: Type 2 diabetes mellitus (T2DM) is one of the significant risk factors for Alzheimer disease (AD). Defects in insulin signaling pathway induce AD hallmarks mainly through activation of glycogen synthase kinase-3β (GSK-3β) pathway. Objectives: In this study, we investigated the expression of GSK-3β and insulin receptor (IR) genes in the hippocampi of an animal model of sporadic AD and assessed the preventive effect of Catechin (CAT) and epigallocatechin gallate (EGCG) on their expression. Materials & Methods: Adult male Wistar rats were treated by intracerebroventricular streptozotocin (STZ) injection (3 mg/kg) at day 1 and 3 after cannulation. CAT was administered at a dose of 40 mg/kg for 10 days per gavage, and EGCG was administered at a dose of 3 mg/kg for 14 days into drinking water. Then the animals were decapitated, and their hippocampi were removed. Real-time Polymerase Chain Reaction (PCR) was used to evaluate the alteration in gene expression. Results: There was overexpression in GSK-3β gene in STZ-treated rats (P≤0.05), which was brought back to normalcy by EGCG (P≤0.01). The IR gene also increased after STZ treatment, but CAT reduced IR expression (P≤0.05). However, the suppressive effect of EGCG on IR expression was stronger (P≤0.01). Conclusion: The neuroprotective activity of EGCG might be due to its influence on IR and GSK-3β expression.
Background This study aimed to investigate the association between Type-1 Diabetes Mellitus and diet in the first two years of life as well as a select group of demographic variables. Methods This case-control study was conducted on 76 children with T1DM and 209 non-diabetic children selected through convenience sampling from the population of people visiting the community health centers of the city of Jahrom, Iran. The required data were collected by a questionnaire of diet and demographic information that was completed by the mothers of the children. The data were analyzed using logistic regression and adjusted odds ratio. Results Finally, the results of multiple backward logistic regression showed that Body Mass Index (BMI) of the mother being less than 18.5 before pregnancy (OR: 4.4, 95% CI: 1.61 to 11.97), mothers without a history of diabetes (OR: 0.02, 95% CI: 0.001 to 0.60), mother’s weight before pregnancy (OR: 0.88, 95% CI: 0.84 to 0.91), mother’s excess weight during pregnancy(OR: 0.83, 95% CI: 0.75 to 0.93), exclusive breastfeeding for more than six months (OR: 0.19, 95% CI: 0.03 to 0.96), low weight gain in the first two years of life (OR: 6.98, 95% CI: 2.16 to 22.5), and the breastfeeding less than 12 months (OR: 10.52, 95% CI: 1.62 to 66.64) have association with Type 1 diabetes (p < 0.05). Conclusion Body mass index less than 18 mothers before pregnancy, Low weight gain in the first two years of life and breastfeeding less than 12 months increases the risk of developing Type-1 Diabetes in children.
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