Objectives: The purpose of the present study was to compare the topical application of chlorohexidine (CHX) and Metronidazole (MTZ) gels, individually and in combination in patients with gingivitis for up to 12 weeks follow-up. Methods: The clinical trial was conducted at Liaquat University of Medical Health Sciences (LUMHS) Jamshoro and Hyderabad, Institute of Dentistry from 1st March 2019 to 1st March 2020. Patients were selected based on inclusion criteria. Out of 125 screened patients, ninety-nine patients agreed to participate in the study. At the beginning of study all patients were assessed for gingival inflammation by using gingival index (GI) (Loe and silness, 1963). Scaling root planning (SRP) was performed in all patients. Subjects were randomly selected in three groups (n=33 each). In Group-A CHX gel was applied, Group-B Metronidazole gel was applied and the combination of two was applied to patients of Group-C. Patient follow up was done and gingival parameters were assessed at baseline, fourth week and twelve weeks. Apart from the clinical evaluation, a subjective evaluation was also undertaken. Significance level of 0.05 and a desired study power of at least 80% was estimated. Analysis of Variance (ANOVA) test for comparison was used within groups. Results: A significant improvement in gingival scores was noted in all groups from baseline. At 4 weeks CHX (1.25±0.21) MTZ (1.81±0.38) CHX+MTZ (1.29±0.34) compared to baseline CHX (2.77±0.24) MTZ (2.84±0.54) CHX+MTZ (2.74±0.31) demonstrated substantial improvement (p<0.001). However, gingival scores showed inclination at 12 weeks CHX (1.18±0.41) MTZ (1.21±0.48) CHX+MTZ (1.11±0.14) with no significant difference to week 4 (p>0.001). Conclusion: Local MTZ gel and MTZ+CHX gel showed effectiveness similar to CHX gel application adjunct to scaling and root planning in the treatment of gingivitis. doi: https://doi.org/10.12669/pjms.37.5.4236 How to cite this:Panhwar M, Rajpar SP, Abrar E, Alqutub M, Abduljabbar T. Effectiveness of Chlorhexidine and Metronidazole Gels in the management of gingivitis. A clinical trial. Pak J Med Sci. 2021;37(5):---------. doi: https://doi.org/10.12669/pjms.37.5.4236 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
ABSTRACT… Objectives: The aim of study to determine the occurrence of gingival recession in younger population of Jamshoro, also to identify its common cause, so that we can able to establish preventive measures. Study Design: Cross-sectional. Setting: Dental OPD at Liaquat University of Medical Health Sciences Jamshoro. Period: 4 months from May, 2017 to October 2017. Material and Methods: Study was done on (300) patients, between 18 to 30 years, before selection, they were examined, only those selected, who have gingival recession, this was done by Miller's Classification, data was obtained by a questionnaire along with the clinical examination. Perform was consists of detailed information of habits and brushing method, scores were given for presence of gingival recession, using Miller's classification. Identification of faulty brushing technique was done by clinical examining. After the completion, all of them were also given suitable treatments also oral hygiene instructions. Results: Mean age of the was 21.09±6.178. Scores of recessions was done according to the classification of Miller, revealed that Class I were the commonest showed 78%, followed by Class II 16%, Class III 4.6% and Class IV 1.4%.Regarding brushing method (horizontal method, medium tooth brush) Statistical analysis revealed that the correlation between both toothbrush type and brushing method and gingival recession were statistically significant (P < 0.001). Conclusion: The accumulation of plaque and wrong brushing method were the commonest causes of recession, educational program for oral health care should be done at community level to reduce its risk. The information from study would help us to made to prevent strategies and therapeutic methods.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.