Two experiments were conducted to evaluate the effect of short transport stress on ewes during dioestrus and pro-oestrus. In Experiment 1, intra-vaginal sponges containing fluorogestone acetate were inserted into ewes for a period of 12 days. A gonadotrophin (PMSG) injection was given at the time of sponge withdrawal to induce oestrous. To dissociate the possible effect of PMSG during prooestrus, a second experiment was designed in which prostaglandin was used as the oestrous induction factor. Ewes in both experiments were subjected to 30 min of transport by truck. In addition, oestrous behaviour and serum cortisol concentration were evaluated. Control groups consisted of untransported ewes. In both experiments, cortisol concentration was greater (P 0n01) in transported than in un-transported animals. No difference (P 0n05) was found between moving the ewes during pro-oestrous or di-oestrus (0n30p0n03 v. 0n53p0n18 ng\ml and 3n88p0n97 v. 2n94p0n73 ng\ml in Experiment 1 and 2 respectively). The number of ewes detected in oestrous was similar (P 0n05) among those stressed during di-oestrus, pro-oestrus or un-transported animals within each experiment (66, 47 and 42 % respectively in Experiment 1 and 96n7 in all situations in Experiment 2). In general, higher cortisol concentration and more ewes displaying oestrous behaviour were detected in Experiment 2. It was concluded that under the conditions of these experiments, no difference was found in the proportion of ewes displaying oestrus regardless of the phase of the oestrous cycle in which they were transported.
La glomerulonefritis de rápida progresión (GNRP) pauciinmunitaria o de tipo III negativa a ANCA es infrecuente y representa tan sólo 10% a 20% del total de las GNRP pauciinmunitarias. Existen diferencias clínicas, analíticas y anatomopatológicas, entre las GNRP pauciinmunitarias negativas y positivas a ANCA. La sospecha de una GNRP pauciinmunitaria negativa a ANCA es elemental, ya que el pronóstico renal es tal vez peor en este subgrupo de pacientes. El tratamiento, al igual que en las GNRP de tipo III positivas a ANCA, se basa en la indicación de glucocorticoides y fármacos inmunosupresores.Palabras clave: Glomerulonefritis pauciinmunitaria. Glomerulonefritis de rápida progresión. Vasculitis negativa a anticuerpo anticitoplasma de neutrófilos (ANCA). Insuficiencia renal aguda. Síndrome nefrótico.
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