Bovine sponge amnion (BSA) is made from bovine amniotic membrane, which contains several growth factors with the ability to suppress inflammation and stimulate the healing process. The healing process of the socket is clinically marked by the proliferation of fibroblasts, formation of new blood vessels, and closure of the wound site. Fibroblasts and new blood vessels are the common histological indicators of tissue regeneration. Twenty-four lower anterior teeth were extracted from the rats. The socket was then applied with BSA and sutured, while a control group was only sutured. The animals were scarified 3, 7, and 14 days after application, and the mandibular was isolated. Histological analysis of socket tissue used the staining of hematoxylin and eosin to analyze the new blood vessels and fibroblasts. An independent t-test was used to analyze the fibroblasts and new blood vessels in each group, with P < 0.05 considered as significant. The number of fibroblasts is higher in the BSA group compared others groups at 3, 7, and 14 days (P < 0.05). The new blood vessel count is higher compared to the control group at only 3 and 7 days (P < 0.05). BSA aids the regeneration of the socket after tooth extraction by stimulating fibroblast proliferation and formation of new blood vessels.
Background: Oral health knowledge, attitudes and behaviors possessed by dental students become provisions in the education and promotion of oral health in the community. Purpose: This study aims to analyze the oral health knowledge, attitudes and behavior of Indonesian dental students in East Java province based on gender and educational stage. Methods: This research is a cross-sectional study using an online questionnaire distributed to dental students at five dental faculties in East Java. 169 respondents in this study completed an online HU-DBI questionnaire with a choice of answers to agree or disagree about the description of oral health knowledge, attitudes, and behavior. Results: Female students have a higher level of knowledge and oral health behavior than the opposite sex with a significance value of <0.001 and 0.05, respectively. There was a significant correlation between knowledge and attitude with a significance level of 0.030 and a correlation between knowledge and behavior with a significant number of 0.037. Conclusion: Female dental students had better oral health knowledge and behavior than male dental students. There is no relationship between the education stage and oral health knowledge, attitudes and behaviour. Further, we found positif association between oral health knowledge and attitudes towards behaviour.
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