Purpose To use a portable 4°C cooled MR‐compatible water calorimeter to measure absorbed dose in a magnetic resonance‐guided radiation therapy (MRgRT) system. Furthermore, to use the calorimetric dose results and direct cross‐calibration to experimentally measure the combined beam quality and magnetic field correction factor (kQmag) of a clinically used reference‐class ionization chamber placed under the same radiation field. Methods An Elekta Unity MR‐linac (7 MV FFF, B = 1.5 T) was used in this study. Measurements were taken using the in‐house designed and built water calorimeter. Following preparation and cooling of the system, the MR‐compatible calorimeter was positioned using a combination of MR and EPID imaging and the dose to water was measured by monitoring the radiation‐induced temperature change. Immediately after the calorimetric measurements, an A1SL ionization chamber was placed inside the calorimeter for direct cross‐calibration. The results allowed for a direct and absolute experimental measurement of kQmag for this chamber and comparison against existing Monte Carlo values. Results The calorimeter was successfully positioned using imaging in under an hour. The 1‐hour setup time is from the time the calorimeter leaves storage to the first calorimetric measurement. Absorbed dose was successfully measured with a relative combined standard uncertainty of 0.71 % (k = 1). Through a cross‐calibration, the kQmag for an Exradin A1SL ionization chamber, set up perpendicular to the incident photon beam and opposite to the direction of the Lorentz force, was directly determined in water in absolute terms to be 0.977 ± 0.010. The currently published kQmag results, obtained via Monte Carlo calculations, agree with experimental measurements in this work within combined uncertainties. Conclusions A novel design of an MR‐compatible water calorimeter was successfully used to measure absorbed dose in an MR‐linac and determine an experimental value of kQmag for a clinically used ionization chamber.
The purpose of this study is to design a water calorimeter with three goals in mind: (a) To be fully magnetic resonance (MR)-compatible; (b) To be imaged using kV cone beam computed tomography (CBCT), MV portal imaging or MRI for accurate positioning; (c) To accommodate both vertical and horizontal beam incidence, as well as volumetric deliveries or Gamma Knife ®. Following this, the calorimeter performance will be measured using an accelerator-based high-energy photon beam. Methods: A portable 4°C cooled stagnant water calorimeter was built using MR-compatible materials. The walls consist of layers of acrylic plastic, aerogel-based material acting as thermal insulation, as well as tubing for coolant to flow to keep the calorimeter temperature stable at 4°C. The lid contains additional pathways for coolant to flow through as well as two hydraulically driven stirrers. The water calorimeter was positioned in an Elekta Versa using kV CBCT imaging as well as orthogonal MV image pairs. Absolute absorbed dose to water was then determined under a 6 MV flattening filter-free (FFF) beam. This was compared against reference dosimetry results that were measured under identical conditions with an Exradin A1SL ionization chamber with a calibration coefficient directly traceable to the National Research Council Canada. Results: The dose to water determined with the calorimeter (n = 30) agreed with the A1SL ionization chamber reference dose measurements (n = 15) to within 0.25%. The uncertainty associated with the water calorimeter absorbed dose measurement was estimated to be 0.54% (k = 1). Conclusions: An MR-compatible water calorimeter was successfully built and absolute absorbed dose to water under a conventional 6 MV FFF beam was determined successfully as a first-stage validation of the system.
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