A Tuberculose, doença infecciosa causada por micobactérias pertencentes ao Complexo M. tuberculosis, consiste num problema de saúde pública, principalmente nas unidades prisionais cujas condições são propicias à incidência deste agravo. O objetivo deste estudo foi analisar a importância da cultura automatizada MGIT® 960 BD ("padrão-ouro"), o desempenho do Teste Rápido Molecular no equipamento GeneXpert® MTB/RIF e a distribuição do quantitativo da tuberculose em cinco unidades prisionais da área de abrangência do CLR IAL PP V, no período entre outubro/2015 e outubro/2016. Foram analisadas 4.509 amostras para diagnóstico, apresentando especificidade de 99,03%, sensibilidade de 72,73% e concordância de 97% entre os testes. Os Resultados mostraram a importância da cultura para identificação de espécie e implantação do TRM-TB na rotina laboratorial, bem como da necessidade de melhoria na qualidade e no quantitativo de amostras coletadas no sistema prisional. Palavras-chave: tuberculose, diagnóstico, cultura, teste rápido molecular, unidade prisional.
This study aims to describe the results of the implementation of the molecular diagnosis of Covid-19 at the Instituto Adolfo Lutz Regional Laboratory Center in Presidente Prudente (CLR IAL PP-V). This is a descriptive observational study carried out from April 2020 to June 2022. The implementation of the diagnosis was only possible from the "Term of Cooperation between the Municipality of P. Prudente and the Public Ministry of Labor -PRT/15th Region/PTM of P. Prudente, with the consent of the Health Department of the State of São Paulo". This term allocated financial resources for the acquisition of equipment, supplies and adaptation of the physical facilities of the laboratory. Additionally, P. Prudente's municipal civil servants were made available and employees were temporarily hired to assist in the laboratory routine. The laboratory for the diagnosis of Covid-19 was opened on August 13, 2020. From its implementation until June 2022, more than 113,000 diagnostic tests for Covid-19 were carried out. While in 2020, approximately 30% of the samples received were analyzed; in 2022, the laboratory performed analyzes of 95% of the total samples received. Carrying out this exam in the CLR IAL PP-V was also important in terms of reducing the time to release the results, which averaged 1.2 days in general from 2020 to 2022, not exceeding 2.5 days. The results of the present study demonstrate the importance of the work of the Adolfo Lutz Institute in the prevention, control and laboratory surveillance of Public Health problems, especially in controlling the spread of the pandemic within its region of coverage.
RESUMO
ACTIVITY OF THE REGIONAL LABORATORY CENTER ADOLFO LUTZ INSTITUTE IN THE QUALITY CONTROL OF THE DIAGNOSIS OF VISCERAL CANINE LEISHMANIASIS ABSTRACTVisceral leishmaniasis (VL) is a serious public health problem and it has expanded in São Paulo territory. Zoonosis caused by the protozoan Leishmania infantum (synonymy-Leishmania chagasi), transmitted, primarily, by the bite of Lutzomyia longipalpis. The present study aimed to analyze the performance of the Adolfo Lutz Institute Regional Laboratory Center of Presidente Prudente, in the quality control of the diagnosis of canine VL, in the period of April/2012 and April/2017. In the analyzed period, 26 training courses were given to 28 municipalities to use the QT DPP BioManguinhos as a screening test for canine VL; 60 technical visits to 25 municipalities and analyzed 1,126 serum samples sent by the municipal zoonoses services for quality control, of which 752 were non-reagent samples and 374 were reagents in the QT DPP BioManguinhos. It is of great importance in Public Health the performance of the regional reference laboratory in the quality control of the canine VL diagnosis.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.