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No abstract

-American Foulbrood (AFB), caused by the spore-forming bacterium Paenibacillus larvae larvae, is the most serious disease of honeybees. Laboratory and field trials were conducted to evaluate the effectiveness of essential oils from savory, thyme, lemon-grass, and oregano, and blends of lemon-grass + thyme; lemon-grass + thyme + oregano + basil, and lemon-grass + thyme + basil in preventing and controlling infections of AFB in Apis mellifera colonies. The principal components of the essential oils used were determined by gas chromatography. LD 50 values for acute oral toxicity of the oils on adult bees verified that the essences were non-toxic or slightly toxic. Results from field trials indicate that neither the essences nor the blends were effective in the elimination of AFB clinical symptoms at any dose formulation or method of administration tested, whereas tylosin was highly effective in eliminating AFB clinical symptoms.American foulbrood / Apis mellifera / Paenibacillus larvae larvae / essential oil / tylosin

The minimal inhibitory concentrations (MICs) of tylosin were determined to 67 strains of Paenibacillus larvae subsp. larvae, the causal agent of American Foulbrood (AFB) disease, from different geographical origins. MIC values obtained ranged from 0.0078 to 0.5 mg/ml. These very low values imply that no resistance to tylosin was found in any isolate of the Foulbrood pathogen.The measurement of diseased larvae with AFB-clinical symptoms in three different field studies demonstrated that tylosin treatment could be effective in vivo. No negative effects in colonies were noted at any dosage rates or forms of application. These studies demonstrate that tylosin, as tartrate, can be used to treat AFB in honeybee colonies. #