This study evaluated the effect of surrounded shade and specimens` thickness on the color adjustment potential (CAP) of a single-shade composite. The composite Vittra APS Unique was surrounded (dual specimens) or not (simple specimens) by a control composite (shade A1, A2, or A3). Simple specimens of the control composite were also confectioned. Opacity and whiteness index for dentistry (WID) were calculated for simple specimens. Color differences between the simple (ΔE*SIMPLE)/ dual specimens (ΔE*DUAL) and the controls were calculated. CAP was calculated based on the ratio between ΔE* SIMPLE and ΔE* DUAL. The tested composite presented lower opacity (53 to 62% vs. 80 to 93%) and higher WID (≈ 42 vs. 18 to 32) than controls. Irrespective of the specimens’ thickness (1.0/ 1.5 mm), the lowest values of ΔE* SIMPLE (11.1/ 10.8) and ΔE*DUAL (7.2/ 6.1) were observed using the surrounding shade A1. The shade A3 yielded higher ΔE*SIMPLE (16.4/ 17.1) and ΔE* DUAL (11.3/ 12.3) than the A2 (ΔE*SIMPLE = 13.4/ 14.6; and ΔE* DUAL = 9.7/ 10.3). The specimen`s thickness significantly affected the CAP (0.35 and 0.44 for 1.0 and 1.5 mm, respectively) only for shade A1, which had the highest CAP values. The shade A3 resulted in higher CAP values (0.31) than A2 (0.27) when 1.0-mm thick specimens were used, but similar values were observed for 1.5 thick specimens (≈ 0.29). In conclusion, both surrounding shade and specimen thickness can affect the CAP of a single-shade resin composite.

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Herpes Zoster (HZ) é uma infecção aguda causada pelo vírus varicela-zoster, quando ocorre reativação do mesmo que está latente em células nervosas de indivíduos que tiveram varicela. O mecanismo da reativação viral ainda é desconhecido, porém acredita-se que esteja relacionado com algum tipo de deficiência na imunidade. A doença afeta mais comumente indivíduos imunossuprimidos e idosos. Clinicamente se caracteriza por lesões vesículo- bolhosas distribuídas na região inervada pelo nervo afetado, causando dores intensas. Este artigo relata dois casos em pacientes idosos que se queixavam de lesões bucais e cutâneas com sintomatologia dolorosa. Em ambos os casos as lesões envolviam o nervo trigêmeo e evoluíram apresentando complicações como a Neuralgia Pós-Herpética e a Síndrome de Ramsay Hunt. Foi prescrito antiviral, analgésico, antibiótico e laserterapia. Em nenhum dos casos ocorreu recidiva no espaço de proservação de 3 anos. O cirurgião-dentista precisa estar atento às lesões vesículo - bolhosas que acometem a pele e as mucosas de forma unilateral, acompanhadas de sintomas de prurido e dor, especialmente em idosos, por apresentarem risco aumentado de desenvolver HZ com complicações e necessidade de hospitalização.

We aimed to evaluate the orofacial antinociceptive effect of geraniol in mice and its molecular anchorage mechanism. Seven mice per group (probabilistic sample) were treated with geraniol (12.5, 25 and 50 mg/kg, i.p.), morphine (6 mg/kg, i.p.) and vehicle (saline + Tween 80 at 0.2%, i.p.) 30 minutes prior to the beginning of the experiment. Injecting glutamate (25 μM), capsaicin (2.5 μg) and formalin (2%) into the right upper lip (perinasal) of the mouse induced nociception. Behavioral analysis of the animals considered the friction time (in seconds) of the mentioned region using hind or front paws by a researcher blinded to the treatment groups. The statistical analysis was performed blindly, considering α = 5%. The results showed that in the glutamate and capsaicin tests, concentrations of 25 mg/kg and 50 mg/ kg presented antinociceptive activity (p < 0.005, power> 80%). In the formalin test, geraniol was able to reduce nociception at a concentration of 50 mg/kg (p < 0.005, power> 80%). In the molecular anchorage study, high values of binding between the evaluated substance and receptors of glutamate were observed (metabotropic glutamate receptor,-87.8501 Kcal/mol; N-methyl-D-aspartate,-86.4451 Kcal/mol; α-amino-3hydroxy-5-methyl-4-isoxazole propionic acid,-85.6755 Kcal/mol). Geraniol presented orofacial antinociceptive activity, probably by interacting with glutamate-related receptors.

Objective Individuals born with cleft lip and palate may face difficulties in speech function, nutrition, facial aesthetics, and long‐term care. These difficulties may increase the risk of psychological and psychiatric diseases. This work aimed to test if the variant allele of COMT was carried more frequently among individuals that have psychological and psychiatric outcomes within a cohort of patients born with cleft lip and palate. Method DNA extraction from saliva of two hundred and fifteen individuals born with cleft lip with and/or palate and genotyping was performed, and the frequency of COMT rs4818 alleles was determined. The domain ‘Psychological Function’ of Cleft‐Q™ was used to generate scores for analysis. The scores were computed, and differences in genotype or allele frequencies between individuals with psychological function scores 60 or above and 59 or below were compared. The history of psychiatric illness (family history of psychiatric disease or self‐reported psychiatric illness) was registered. Results Genotype and allele frequencies were compared between individuals with and without a family history of psychiatric illness. Individuals with lower Psychological Function (Cleft‐Q™) scores were more likely to be GG (P = .04) or carriers of allele G (P < .001). The reported psychiatric illness and positive family history of psychiatric illness were compared to COMT rs4818 allele and genotype frequencies of individuals without these indicators, and individuals with psychiatric illness and positive family history of psychiatric illness were more likely to carry allele G (P = .03 and P = .008, respectively). Conclusion The study confirms previously suggested role of COMT rs4818 in psychiatric and psychological outcomes in a distinct cohort of patients born with cleft lip and palate.

Maxillary sinus lifting is a procedure for bone height gain in atrophic jaws. New safe and less complex manners have been evalueted, which use modifications of conventional techniques, through technologies such as devices and equipment that make them less traumatic. This study aims to conduct a literature review of articles found in the PubMed database between the years 2015 and 2020 that addresses advances in Maxillary sinus lifting techniques. We noticed that there is a development in the techniques that promotes the reduction of operative time, perforations and consequently a better postoperative for the patient, reducing the unpleasant perception of the surgery. The use of surgical ultrasound reduces the trauma to the soft tissues and the number of membrane perforations. A great step in the development of the sinus membrane lifting technique was the perception that bone formation is possible with the detachment of the membrane, not requiring the placement of a graft. There is no technique that replaces Maxillary Sinus Lifting yet. Only to improve it.

Introdução: A perspectiva do paciente com fissura labiopalatina (FLP) é importante para avaliar resultados obtidos nos tratamentos, podendo contribuir para melhor qualidade de vida. Objetivos: Através do CLEFT-Q, avaliar a influência do tratamento na qualidade de vida do paciente. Métodos: Estudo transversal observacional, com 100 indivíduos com FLP, os quais responderam o CLEFT-Q. Resultados: A média de idade dos participantes foi 16±4,9 anos. O tipo de FLP mais frequente foi o transforame, com 85%. Os tratamentos realizados foram: queiloplastia, palatoplastia, enxerto ósseo, rinoplastia e tratamento ortodôntico. Os escores CLEFT-Q mais baixos foram nas Escalas de Aparência, relacionados à aparência do nariz e narinas e, os maiores foram nas Escalas de Qualidade de vida, relacionados a aspectos psicológico e escolar.  Houve correlação estatisticamente significante entre os tratamentos e pelo menos uma Escala nos domínios Aparência, Qualidade de vida e Função facial, exceto para rinoplastia.  O tratamento ortodôntico teve correlação negativa com todos os domínios, com associação estatisticamente significante nas Escalas face, narinas, dentes, lábios, dificuldade da fala, escolar, social e fala, exceto para nariz, psicológico e comer/beber. A escala fala teve correlação estatisticamente significante com palatoplastia, enxerto ósseo e tratamento ortodôntico e, a Escala comer/beber teve com enxerto ósseo. Conclusões: Pacientes com FLP sentem insatisfação com sua aparência facial, especialmente, quanto ao nariz, narinas e dentes. Os tratamentos impactaram na percepção do paciente quanto a aparência, qualidade de vida relacionada à saúde e função facial. A queiloplastia e o enxerto ósseo impactaram positivamente na qualidade de vida do paciente com FLP.